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Differential Kinase Activity Across Prostate Tumor Compartments Defines Sensitivity to Target Inhibition.
Karabacak NM, Zheng Y, Dubash TD, Burr R, Micalizzi DS, Wittner BS, Lin M, Wiley DF, Comaills V, Emmons E, Niederhoffer KL, Ho U, Ukleja J, Che D, Stowe H, Nieman LT, Haas W, Stott SL, Lawrence MS, Ting DT, Miyamoto DT, Haber DA, Toner M, Maheswaran S. Karabacak NM, et al. Among authors: burr r. Cancer Res. 2022 Mar 15;82(6):1084-1097. doi: 10.1158/0008-5472.CAN-21-2609. Cancer Res. 2022. PMID: 35045985 Free PMC article.
COX-2 mediates tumor-stromal prolactin signaling to initiate tumorigenesis.
Zheng Y, Comaills V, Burr R, Boulay G, Miyamoto DT, Wittner BS, Emmons E, Sil S, Koulopoulos MW, Broderick KT, Tai E, Rengarajan S, Kulkarni AS, Shioda T, Wu CL, Ramaswamy S, Ting DT, Toner M, Rivera MN, Maheswaran S, Haber DA. Zheng Y, et al. Among authors: burr r. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5223-5232. doi: 10.1073/pnas.1819303116. Epub 2019 Feb 28. Proc Natl Acad Sci U S A. 2019. PMID: 30819896 Free PMC article.
The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis.
Hong X, Roh W, Sullivan RJ, Wong KHK, Wittner BS, Guo H, Dubash TD, Sade-Feldman M, Wesley B, Horwitz E, Boland GM, Marvin DL, Bonesteel T, Lu C, Aguet F, Burr R, Freeman SS, Parida L, Calhoun K, Jewett MK, Nieman LT, Hacohen N, Näär AM, Ting DT, Toner M, Stott SL, Getz G, Maheswaran S, Haber DA. Hong X, et al. Among authors: burr r. Cancer Discov. 2021 Mar;11(3):678-695. doi: 10.1158/2159-8290.CD-19-1500. Epub 2020 Nov 17. Cancer Discov. 2021. PMID: 33203734 Free PMC article.
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer.
Guo H, Golczer G, Wittner BS, Langenbucher A, Zachariah M, Dubash TD, Hong X, Comaills V, Burr R, Ebright RY, Horwitz E, Vuille JA, Hajizadeh S, Wiley DF, Reeves BA, Zhang JM, Niederhoffer KL, Lu C, Wesley B, Ho U, Nieman LT, Toner M, Vasudevan S, Zou L, Mostoslavsky R, Maheswaran S, Lawrence MS, Haber DA. Guo H, et al. Among authors: burr r. Mol Cell. 2021 Oct 7;81(19):4041-4058.e15. doi: 10.1016/j.molcel.2021.09.016. Mol Cell. 2021. PMID: 34624217 Free PMC article.
284 results