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Altered histone acetylation is associated with age-dependent memory impairment in mice.
Peleg S, Sananbenesi F, Zovoilis A, Burkhardt S, Bahari-Javan S, Agis-Balboa RC, Cota P, Wittnam JL, Gogol-Doering A, Opitz L, Salinas-Riester G, Dettenhofer M, Kang H, Farinelli L, Chen W, Fischer A. Peleg S, et al. Among authors: burkhardt s. Science. 2010 May 7;328(5979):753-6. doi: 10.1126/science.1186088. Science. 2010. PMID: 20448184
A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories.
Agis-Balboa RC, Arcos-Diaz D, Wittnam J, Govindarajan N, Blom K, Burkhardt S, Haladyniak U, Agbemenyah HY, Zovoilis A, Salinas-Riester G, Opitz L, Sananbenesi F, Fischer A. Agis-Balboa RC, et al. Among authors: burkhardt s. EMBO J. 2011 Aug 26;30(19):4071-83. doi: 10.1038/emboj.2011.293. EMBO J. 2011. PMID: 21873981 Free PMC article.
microRNA-34c is a novel target to treat dementias.
Zovoilis A, Agbemenyah HY, Agis-Balboa RC, Stilling RM, Edbauer D, Rao P, Farinelli L, Delalle I, Schmitt A, Falkai P, Bahari-Javan S, Burkhardt S, Sananbenesi F, Fischer A. Zovoilis A, et al. Among authors: burkhardt s. EMBO J. 2011 Sep 23;30(20):4299-308. doi: 10.1038/emboj.2011.327. EMBO J. 2011. PMID: 21946562 Free PMC article.
HDAC1 regulates fear extinction in mice.
Bahari-Javan S, Maddalena A, Kerimoglu C, Wittnam J, Held T, Bähr M, Burkhardt S, Delalle I, Kügler S, Fischer A, Sananbenesi F. Bahari-Javan S, et al. Among authors: burkhardt s. J Neurosci. 2012 Apr 11;32(15):5062-73. doi: 10.1523/JNEUROSCI.0079-12.2012. J Neurosci. 2012. PMID: 22496552 Free PMC article.
Histone-methyltransferase MLL2 (KMT2B) is required for memory formation in mice.
Kerimoglu C, Agis-Balboa RC, Kranz A, Stilling R, Bahari-Javan S, Benito-Garagorri E, Halder R, Burkhardt S, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: burkhardt s. J Neurosci. 2013 Feb 20;33(8):3452-64. doi: 10.1523/JNEUROSCI.3356-12.2013. J Neurosci. 2013. PMID: 23426673 Free PMC article.
Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia.
Agís-Balboa RC, Pinheiro PS, Rebola N, Kerimoglu C, Benito E, Gertig M, Bahari-Javan S, Jain G, Burkhardt S, Delalle I, Jatzko A, Dettenhofer M, Zunszain PA, Schmitt A, Falkai P, Pape JC, Binder EB, Mulle C, Fischer A, Sananbenesi F. Agís-Balboa RC, et al. Among authors: burkhardt s. EMBO J. 2017 Oct 2;36(19):2815-2828. doi: 10.15252/embj.201796821. Epub 2017 Aug 2. EMBO J. 2017. PMID: 28768717 Free PMC article.
KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.
Kerimoglu C, Sakib MS, Jain G, Benito E, Burkhardt S, Capece V, Kaurani L, Halder R, Agís-Balboa RC, Stilling R, Urbanke H, Kranz A, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: burkhardt s. Cell Rep. 2017 Jul 18;20(3):538-548. doi: 10.1016/j.celrep.2017.06.072. Cell Rep. 2017. PMID: 28723559 Free article.
K-Lysine acetyltransferase 2a regulates a hippocampal gene expression network linked to memory formation.
Stilling RM, Rönicke R, Benito E, Urbanke H, Capece V, Burkhardt S, Bahari-Javan S, Barth J, Sananbenesi F, Schütz AL, Dyczkowski J, Martinez-Hernandez A, Kerimoglu C, Dent SY, Bonn S, Reymann KG, Fischer A. Stilling RM, et al. Among authors: burkhardt s. EMBO J. 2014 Sep 1;33(17):1912-27. doi: 10.15252/embj.201487870. Epub 2014 Jul 14. EMBO J. 2014. PMID: 25024434 Free PMC article.
145 results