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MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors.
Kilian M, Sheinin R, Tan CL, Friedrich M, Krämer C, Kaminitz A, Sanghvi K, Lindner K, Chih YC, Cichon F, Richter B, Jung S, Jähne K, Ratliff M, Prins RM, Etminan N, von Deimling A, Wick W, Madi A, Bunse L, Platten M. Kilian M, et al. Among authors: bunse l. Cancer Cell. 2023 Feb 13;41(2):235-251.e9. doi: 10.1016/j.ccell.2022.12.007. Epub 2023 Jan 12. Cancer Cell. 2023. PMID: 36638785 Free article.
mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy.
Weiler M, Blaes J, Pusch S, Sahm F, Czabanka M, Luger S, Bunse L, Solecki G, Eichwald V, Jugold M, Hodecker S, Osswald M, Meisner C, Hielscher T, Rübmann P, Pfenning PN, Ronellenfitsch M, Kempf T, Schnölzer M, Abdollahi A, Lang F, Bendszus M, von Deimling A, Winkler F, Weller M, Vajkoczy P, Platten M, Wick W. Weiler M, et al. Among authors: bunse l. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):409-14. doi: 10.1073/pnas.1314469111. Epub 2013 Dec 23. Proc Natl Acad Sci U S A. 2014. PMID: 24367102 Free PMC article.
A vaccine targeting mutant IDH1 induces antitumour immunity.
Schumacher T, Bunse L, Pusch S, Sahm F, Wiestler B, Quandt J, Menn O, Osswald M, Oezen I, Ott M, Keil M, Balß J, Rauschenbach K, Grabowska AK, Vogler I, Diekmann J, Trautwein N, Eichmüller SB, Okun J, Stevanović S, Riemer AB, Sahin U, Friese MA, Beckhove P, von Deimling A, Wick W, Platten M. Schumacher T, et al. Among authors: bunse l. Nature. 2014 Aug 21;512(7514):324-7. doi: 10.1038/nature13387. Epub 2014 Jun 25. Nature. 2014. PMID: 25043048
Proximity ligation assay evaluates IDH1R132H presentation in gliomas.
Bunse L, Schumacher T, Sahm F, Pusch S, Oezen I, Rauschenbach K, Gonzalez M, Solecki G, Osswald M, Capper D, Wiestler B, Winkler F, Herold-Mende C, von Deimling A, Wick W, Platten M. Bunse L, et al. J Clin Invest. 2015 Feb;125(2):593-606. doi: 10.1172/JCI77780. Epub 2015 Jan 2. J Clin Invest. 2015. PMID: 25555220 Free PMC article. Clinical Trial.
Mutant IDH1: An immunotherapeutic target in tumors.
Schumacher T, Bunse L, Wick W, Platten M. Schumacher T, et al. Among authors: bunse l. Oncoimmunology. 2015 Jan 7;3(12):e974392. doi: 10.4161/2162402X.2014.974392. eCollection 2014 Dec. Oncoimmunology. 2015. PMID: 25964867 Free PMC article.
Concepts in glioma immunotherapy.
Platten M, Bunse L, Wick W, Bunse T. Platten M, et al. Among authors: bunse l, bunse t. Cancer Immunol Immunother. 2016 Oct;65(10):1269-75. doi: 10.1007/s00262-016-1874-x. Epub 2016 Jul 26. Cancer Immunol Immunother. 2016. PMID: 27460064 Free PMC article. Review.
K27M-mutant histone-3 as a novel target for glioma immunotherapy.
Ochs K, Ott M, Bunse T, Sahm F, Bunse L, Deumelandt K, Sonner JK, Keil M, von Deimling A, Wick W, Platten M. Ochs K, et al. Among authors: bunse l, bunse t. Oncoimmunology. 2017 May 12;6(7):e1328340. doi: 10.1080/2162402X.2017.1328340. eCollection 2017. Oncoimmunology. 2017. PMID: 28811969 Free PMC article.
The promises of immunotherapy in gliomas.
Mildenberger I, Bunse L, Ochs K, Platten M. Mildenberger I, et al. Among authors: bunse l. Curr Opin Neurol. 2017 Dec;30(6):650-658. doi: 10.1097/WCO.0000000000000491. Curr Opin Neurol. 2017. PMID: 28984704 Review.
50 results