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BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation.
Raffel S, Falcone M, Kneisel N, Hansson J, Wang W, Lutz C, Bullinger L, Poschet G, Nonnenmacher Y, Barnert A, Bahr C, Zeisberger P, Przybylla A, Sohn M, Tönjes M, Erez A, Adler L, Jensen P, Scholl C, Fröhling S, Cocciardi S, Wuchter P, Thiede C, Flörcken A, Westermann J, Ehninger G, Lichter P, Hiller K, Hell R, Herrmann C, Ho AD, Krijgsveld J, Radlwimmer B, Trumpp A. Raffel S, et al. Among authors: bullinger l. Nature. 2017 Nov 16;551(7680):384-388. doi: 10.1038/nature24294. Epub 2017 Nov 8. Nature. 2017. PMID: 29144447
Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis.
Arends CM, Galan-Sousa J, Hoyer K, Chan W, Jäger M, Yoshida K, Seemann R, Noerenberg D, Waldhueter N, Fleischer-Notter H, Christen F, Schmitt CA, Dörken B, Pelzer U, Sinn M, Zemojtel T, Ogawa S, Märdian S, Schreiber A, Kunitz A, Krüger U, Bullinger L, Mylonas E, Frick M, Damm F. Arends CM, et al. Among authors: bullinger l. Leukemia. 2018 Sep;32(9):1908-1919. doi: 10.1038/s41375-018-0047-7. Epub 2018 Mar 1. Leukemia. 2018. PMID: 29491455
TFE3 activation in a TSC1-altered malignant PEComa: challenging the dichotomy of the underlying pathogenic mechanisms.
Schmiester M, Dolnik A, Kornak U, Pfitzner B, Hummel M, Treue D, Hartmann A, Agaimy A, Weyerer V, Lekaj A, Brakemeier S, Peters R, Öllinger R, Märdian S, Bullinger L, Striefler JK, Flörcken A. Schmiester M, et al. Among authors: bullinger l. J Pathol Clin Res. 2021 Jan;7(1):3-9. doi: 10.1002/cjp2.187. Epub 2020 Nov 12. J Pathol Clin Res. 2021. PMID: 33180365 Free PMC article.
Clinical outcome of older adults with acute myeloid Leukemia: An analysis of a large tertiary referral Center over two decades.
Ihlow J, Gross S, Neuendorff NR, Busack L, Herneth A, Singh A, Schwarz M, Flörcken A, Anagnostopoulos I, Türkmen S, Burmeister T, Blau IW, Bullinger L, Westermann J. Ihlow J, et al. Among authors: bullinger l. J Geriatr Oncol. 2021 May;12(4):540-549. doi: 10.1016/j.jgo.2020.11.001. Epub 2020 Nov 19. J Geriatr Oncol. 2021. PMID: 33223482
Impact of a specialised palliative care intervention in patients with advanced soft tissue sarcoma - a single-centre retrospective analysis.
Brandes F, Striefler JK, Dörr A, Schmiester M, Märdian S, Koulaxouzidis G, Kaul D, Behzadi A, Thuss-Patience P, Ahn J, Pelzer U, Bullinger L, Flörcken A. Brandes F, et al. Among authors: bullinger l. BMC Palliat Care. 2021 Jan 14;20(1):16. doi: 10.1186/s12904-020-00702-1. BMC Palliat Care. 2021. PMID: 33446180 Free PMC article.
A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: Results from the CONKO-005 trial.
Hoyer K, Hablesreiter R, Inoue Y, Yoshida K, Briest F, Christen F, Kakiuchi N, Yoshizato T, Shiozawa Y, Shiraishi Y, Striefler JK, Bischoff S, Lohneis P, Putter H, Blau O, Keilholz U, Bullinger L, Pelzer U, Hummel M, Riess H, Ogawa S, Sinn M, Damm F. Hoyer K, et al. Among authors: bullinger l. EBioMedicine. 2021 Apr;66:103327. doi: 10.1016/j.ebiom.2021.103327. Epub 2021 Apr 13. EBioMedicine. 2021. PMID: 33862582 Free PMC article. Clinical Trial.
Acute myeloid leukemia: negative prognostic impact of early blast persistence can be in part overcome by a later remission prior to post-induction therapy.
Ihlow J, Gross S, Busack L, Flörcken A, Jesse J, Schwarz M, Neuendorff NR, Brünneck AV, Anagnostopoulos I, Türkmen S, Blau IW, Burmeister T, Horst D, Bullinger L, Westermann J. Ihlow J, et al. Among authors: bullinger l. Haematologica. 2022 Aug 1;107(8):1773-1785. doi: 10.3324/haematol.2021.279134. Haematologica. 2022. PMID: 34758607 Free PMC article.
385 results