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The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease.
Rogaeva E, Meng Y, Lee JH, Gu Y, Kawarai T, Zou F, Katayama T, Baldwin CT, Cheng R, Hasegawa H, Chen F, Shibata N, Lunetta KL, Pardossi-Piquard R, Bohm C, Wakutani Y, Cupples LA, Cuenco KT, Green RC, Pinessi L, Rainero I, Sorbi S, Bruni A, Duara R, Friedland RP, Inzelberg R, Hampe W, Bujo H, Song YQ, Andersen OM, Willnow TE, Graff-Radford N, Petersen RC, Dickson D, Der SD, Fraser PE, Schmitt-Ulms G, Younkin S, Mayeux R, Farrer LA, St George-Hyslop P. Rogaeva E, et al. Among authors: bujo h. Nat Genet. 2007 Feb;39(2):168-77. doi: 10.1038/ng1943. Epub 2007 Jan 14. Nat Genet. 2007. PMID: 17220890 Free PMC article.
SORL1 genetic variants and cerebrospinal fluid biomarkers of Alzheimer’s disease.
Guo LH, Westerteicher C, Wang XH, Kratzer M, Tsolakidou A, Jiang M, Grimmer T, Laws SM, Alexopoulos P, Bujo H, Kurz A, Perneczky R. Guo LH, et al. Among authors: bujo h. Eur Arch Psychiatry Clin Neurosci. 2012 Sep;262(6):529-34. doi: 10.1007/s00406-012-0295-x. Eur Arch Psychiatry Clin Neurosci. 2012. PMID: 22286501
β-Site amyloid precursor protein-cleaving enzyme 1 activity is related to cerebrospinal fluid concentrations of sortilin-related receptor with A-type repeats, soluble amyloid precursor protein, and tau.
Tsolakidou A, Alexopoulos P, Guo LH, Grimmer T, Westerteicher C, Kratzer M, Jiang M, Bujo H, Roselli F, Leante MR, Livrea P, Kurz A, Perneczky R. Tsolakidou A, et al. Among authors: bujo h. Alzheimers Dement. 2013 Jul;9(4):386-91. doi: 10.1016/j.jalz.2012.01.015. Epub 2012 Nov 3. Alzheimers Dement. 2013. PMID: 23127467
Loss of apolipoprotein E receptor LR11 in Alzheimer disease.
Scherzer CR, Offe K, Gearing M, Rees HD, Fang G, Heilman CJ, Schaller C, Bujo H, Levey AI, Lah JJ. Scherzer CR, et al. Among authors: bujo h. Arch Neurol. 2004 Aug;61(8):1200-5. doi: 10.1001/archneur.61.8.1200. Arch Neurol. 2004. PMID: 15313836
Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans.
Whittle AJ, Jiang M, Peirce V, Relat J, Virtue S, Ebinuma H, Fukamachi I, Yamaguchi T, Takahashi M, Murano T, Tatsuno I, Takeuchi M, Nakaseko C, Jin W, Jin Z, Campbell M, Schneider WJ, Vidal-Puig A, Bujo H. Whittle AJ, et al. Among authors: bujo h. Nat Commun. 2015 Nov 20;6:8951. doi: 10.1038/ncomms9951. Nat Commun. 2015. PMID: 26584636 Free PMC article.
Crystallization and preliminary crystallographic analysis of human LR11 Vps10p domain.
Nakata Z, Nagae M, Yasui N, Bujo H, Nogi T, Takagi J. Nakata Z, et al. Among authors: bujo h. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jan 1;67(Pt 1):129-32. doi: 10.1107/S1744309110048153. Epub 2010 Dec 23. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21206043 Free PMC article.
221 results