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An experimental approach probing the conformational transitions and energy landscape of antibodies: a glimmer of hope for reviving lost therapeutic candidates using ionic liquid.
Shmool TA, Martin LK, Bui-Le L, Moya-Ramirez I, Kotidis P, Matthews RP, Venter GA, Kontoravdi C, Polizzi KM, Hallett JP. Shmool TA, et al. Among authors: bui le l. Chem Sci. 2021 Jun 22;12(27):9528-9545. doi: 10.1039/d1sc02520a. eCollection 2021 Jul 14. Chem Sci. 2021. PMID: 34349928 Free PMC article.