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Total Synthesis of the Spider-Venom Peptide Hi1a.
Org Lett. 2021 Nov 5;23(21):8375-8379. doi: 10.1021/acs.orglett.1c03112. Epub 2021 Oct 11.
Org Lett. 2021.
PMID: 34632783
Mambalgin-3 potentiates human acid-sensing ion channel 1b under mild to moderate acidosis: Implications as an analgesic lead.
Cristofori-Armstrong B, Budusan E, Rash LD.
Cristofori-Armstrong B, et al. Among authors: budusan e.
Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2021581118. doi: 10.1073/pnas.2021581118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33602819
Free PMC article.
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Hi1a Improves Sensorimotor Deficit following Endothelin-1-Induced Stroke in Rats but Does Not Improve Functional Outcomes following Filament-Induced Stroke in Mice.
Knezic A, Budusan E, Saez NJ, Broughton BRS, Rash LD, King GF, Widdop RE, McCarthy CA.
Knezic A, et al. Among authors: budusan e.
ACS Pharmacol Transl Sci. 2024 Mar 14;7(4):1043-1054. doi: 10.1021/acsptsci.3c00328. eCollection 2024 Apr 12.
ACS Pharmacol Transl Sci. 2024.
PMID: 38638162
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The funnel-web spider venom derived single knot peptide Hc3a modulates acid-sensing ion channel 1a desensitisation.
Budusan E, Payne CD, Gonzalez TI, Obergrussberger A, Becker N, Clark RJ, Johan Rosengren K, Rash LD, Cristofori-Armstrong B.
Budusan E, et al.
Biochem Pharmacol. 2024 Mar 27:116175. doi: 10.1016/j.bcp.2024.116175. Online ahead of print.
Biochem Pharmacol. 2024.
PMID: 38552850
Free article.
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Evaluation of Peptide Ligation Strategies for the Synthesis of the Bivalent Acid-Sensing Ion Channel Inhibitor Hi1a.
Tran HNT, Budusan E, Saez NJ, Norman A, Tucker IJ, King GF, Payne RJ, Rash LD, Vetter I, Schroeder CI.
Tran HNT, et al. Among authors: budusan e.
Org Lett. 2023 Jun 23;25(24):4439-4444. doi: 10.1021/acs.orglett.3c01346. Epub 2023 Jun 12.
Org Lett. 2023.
PMID: 37306339
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CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.
Michlits G, Hubmann M, Wu SH, Vainorius G, Budusan E, Zhuk S, Burkard TR, Novatchkova M, Aichinger M, Lu Y, Reece-Hoyes J, Nitsch R, Schramek D, Hoepfner D, Elling U.
Michlits G, et al. Among authors: budusan e.
Nat Methods. 2017 Dec;14(12):1191-1197. doi: 10.1038/nmeth.4466. Epub 2017 Oct 16.
Nat Methods. 2017.
PMID: 29039415
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