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Synthesis and toxicopharmacological evaluation of m-hydroxymexiletine, the first metabolite of mexiletine more potent than the parent compound on voltage-gated sodium channels.
Catalano A, Desaphy JF, Lentini G, Carocci A, Di Mola A, Bruno C, Carbonara R, De Palma A, Budriesi R, Ghelardini C, Perrone MG, Colabufo NA, Conte Camerino D, Franchini C. Catalano A, et al. Among authors: budriesi r. J Med Chem. 2012 Feb 9;55(3):1418-22. doi: 10.1021/jm201197z. Epub 2012 Jan 31. J Med Chem. 2012. PMID: 22191686
Antiinflammatory effect of phytosterols in experimental murine colitis model: prevention, induction, remission study.
Aldini R, Micucci M, Cevenini M, Fato R, Bergamini C, Nanni C, Cont M, Camborata C, Spinozzi S, Montagnani M, Roda G, D'Errico-Grigioni A, Rosini F, Roda A, Mazzella G, Chiarini A, Budriesi R. Aldini R, et al. Among authors: budriesi r. PLoS One. 2014 Sep 30;9(9):e108112. doi: 10.1371/journal.pone.0108112. eCollection 2014. PLoS One. 2014. PMID: 25268769 Free PMC article.
Playing with opening and closing of heterocycles: using the cusmano-ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and P-glycoprotein inhibitors.
Spinelli D, Budriesi R, Cosimelli B, Severi E, Micucci M, Baroni M, Fusi F, Ioan P, Cross S, Frosini M, Saponara S, Matucci R, Rosano C, Viale M, Chiarini A, Carosati E. Spinelli D, et al. Among authors: budriesi r. Molecules. 2014 Oct 14;19(10):16543-72. doi: 10.3390/molecules191016543. Molecules. 2014. PMID: 25317581 Free PMC article.
126 results