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Resetting proteostasis with ISRIB promotes epithelial differentiation to attenuate pulmonary fibrosis.
Watanabe S, Markov NS, Lu Z, Piseaux Aillon R, Soberanes S, Runyan CE, Ren Z, Grant RA, Maciel M, Abdala-Valencia H, Politanska Y, Nam K, Sichizya L, Kihshen HG, Joshi N, McQuattie-Pimentel AC, Gruner KA, Jain M, Sznajder JI, Morimoto RI, Reyfman PA, Gottardi CJ, Budinger GRS, Misharin AV. Watanabe S, et al. Among authors: budinger grs. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2101100118. doi: 10.1073/pnas.2101100118. Proc Natl Acad Sci U S A. 2021. PMID: 33972447 Free PMC article.
To live or die: a critical decision for the lung.
Budinger GR, Sznajder JI. Budinger GR, et al. J Clin Invest. 2005 Apr;115(4):828-30. doi: 10.1172/JCI24681. J Clin Invest. 2005. PMID: 15841170 Free PMC article.
Proapoptotic Bid is required for pulmonary fibrosis.
Budinger GR, Mutlu GM, Eisenbart J, Fuller AC, Bellmeyer AA, Baker CM, Wilson M, Ridge K, Barrett TA, Lee VY, Chandel NS. Budinger GR, et al. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4604-9. doi: 10.1073/pnas.0507604103. Epub 2006 Mar 14. Proc Natl Acad Sci U S A. 2006. PMID: 16537427 Free PMC article.
209 results