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A spatially restricted fibrotic niche in pulmonary fibrosis is sustained by M-CSF/M-CSFR signalling in monocyte-derived alveolar macrophages.
Joshi N, Watanabe S, Verma R, Jablonski RP, Chen CI, Cheresh P, Markov NS, Reyfman PA, McQuattie-Pimentel AC, Sichizya L, Lu Z, Piseaux-Aillon R, Kirchenbuechler D, Flozak AS, Gottardi CJ, Cuda CM, Perlman H, Jain M, Kamp DW, Budinger GRS, Misharin AV. Joshi N, et al. Among authors: budinger grs. Eur Respir J. 2020 Jan 16;55(1):1900646. doi: 10.1183/13993003.00646-2019. Print 2020 Jan. Eur Respir J. 2020. PMID: 31601718 Free PMC article.
Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway.
Mutlu GM, Green D, Bellmeyer A, Baker CM, Burgess Z, Rajamannan N, Christman JW, Foiles N, Kamp DW, Ghio AJ, Chandel NS, Dean DA, Sznajder JI, Budinger GR. Mutlu GM, et al. J Clin Invest. 2007 Oct;117(10):2952-61. doi: 10.1172/JCI30639. J Clin Invest. 2007. PMID: 17885684 Free PMC article.
Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution.
Soberanes S, Urich D, Baker CM, Burgess Z, Chiarella SE, Bell EL, Ghio AJ, De Vizcaya-Ruiz A, Liu J, Ridge KM, Kamp DW, Chandel NS, Schumacker PT, Mutlu GM, Budinger GR. Soberanes S, et al. J Biol Chem. 2009 Jan 23;284(4):2176-86. doi: 10.1074/jbc.M808844200. Epub 2008 Nov 25. J Biol Chem. 2009. PMID: 19033436 Free PMC article.
209 results