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Preclinical toxicity analyses of lentiviral vectors expressing the HIV-1 LTR-specific designer-recombinase Brec1.
Beschorner N, Künzle P, Voges M, Hauber I, Indenbirken D, Nakel J, Virdi S, Bradtke P, Lory NC, Rothe M, Paszkowski-Rogacz M, Buchholz F, Grundhoff A, Schambach A, Thirion C, Mittrücker HW, Schulze Zur Wiesch J, Hauber J, Chemnitz J. Beschorner N, et al. Among authors: buchholz f. PLoS One. 2024 Mar 8;19(3):e0298542. doi: 10.1371/journal.pone.0298542. eCollection 2024. PLoS One. 2024. PMID: 38457474 Free PMC article.
Activation of recombinases at specific DNA loci by zinc-finger domain insertions.
Mukhametzyanova L, Schmitt LT, Torres-Rivera J, Rojo-Romanos T, Lansing F, Paszkowski-Rogacz M, Hollak H, Brux M, Augsburg M, Schneider PM, Buchholz F. Mukhametzyanova L, et al. Among authors: buchholz f. Nat Biotechnol. 2024 Jan 31. doi: 10.1038/s41587-023-02121-y. Online ahead of print. Nat Biotechnol. 2024. PMID: 38297187
Quantification of evolved DNA-editing enzymes at scale with DEQSeq.
Schmitt LT, Schneider A, Posorski J, Lansing F, Jelicic M, Jain M, Sayed S, Buchholz F, Sürün D. Schmitt LT, et al. Among authors: buchholz f. Genome Biol. 2023 Nov 6;24(1):254. doi: 10.1186/s13059-023-03097-3. Genome Biol. 2023. PMID: 37932818 Free PMC article.
Machine learning-based classification of Alzheimer's disease and its at-risk states using personality traits, anxiety, and depression.
Waschkies KF, Soch J, Darna M, Richter A, Altenstein S, Beyle A, Brosseron F, Buchholz F, Butryn M, Dobisch L, Ewers M, Fliessbach K, Gabelin T, Glanz W, Goerss D, Gref D, Janowitz D, Kilimann I, Lohse A, Munk MH, Rauchmann BS, Rostamzadeh A, Roy N, Spruth EJ, Dechent P, Heneka MT, Hetzer S, Ramirez A, Scheffler K, Buerger K, Laske C, Perneczky R, Peters O, Priller J, Schneider A, Spottke A, Teipel S, Düzel E, Jessen F, Wiltfang J, Schott BH, Kizilirmak JM. Waschkies KF, et al. Among authors: buchholz f. Int J Geriatr Psychiatry. 2023 Oct;38(10):e6007. doi: 10.1002/gps.6007. Int J Geriatr Psychiatry. 2023. PMID: 37800601
218 results