Bu X - Search Results

1

Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade.

Dai X, Bu X, Gao Y, Guo J, Hu J, Jiang C, Zhang Z, Xu K, Duan J, He S, Zhang J, Wan L, Liu T, Zhou X, Hung MC, Freeman GJ, Wei W. Dai X, et al. Among authors: bu x. Mol Cell. 2021 Jun 3;81(11):2317-2331.e6. doi: 10.1016/j.molcel.2021.03.037. Epub 2021 Apr 27. Mol Cell. 2021. PMID: 33909988 Free PMC article.

2

T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells.

DeKruyff RH, Bu X, Ballesteros A, Santiago C, Chim YL, Lee HH, Karisola P, Pichavant M, Kaplan GG, Umetsu DT, Freeman GJ, Casasnovas JM. DeKruyff RH, et al. Among authors: bu x. J Immunol. 2010 Feb 15;184(4):1918-30. doi: 10.4049/jimmunol.0903059. Epub 2010 Jan 18. J Immunol. 2010. PMID: 20083673 Free PMC article.

3

Apoptotic cells activate NKT cells through T cell Ig-like mucin-like-1 resulting in airway hyperreactivity.

Lee HH, Meyer EH, Goya S, Pichavant M, Kim HY, Bu X, Umetsu SE, Jones JC, Savage PB, Iwakura Y, Casasnovas JM, Kaplan G, Freeman GJ, DeKruyff RH, Umetsu DT. Lee HH, et al. Among authors: bu x. J Immunol. 2010 Nov 1;185(9):5225-35. doi: 10.4049/jimmunol.1001116. Epub 2010 Oct 1. J Immunol. 2010. PMID: 20889552 Free PMC article.

4

RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance.

Xiao Y, Yu S, Zhu B, Bedoret D, Bu X, Francisco LM, Hua P, Duke-Cohan JS, Umetsu DT, Sharpe AH, DeKruyff RH, Freeman GJ. Xiao Y, et al. Among authors: bu x. J Exp Med. 2014 May 5;211(5):943-59. doi: 10.1084/jem.20130790. Epub 2014 Apr 21. J Exp Med. 2014. PMID: 24752301 Free PMC article.

5

Learning from PD-1 Resistance: New Combination Strategies.

Bu X, Mahoney KM, Freeman GJ. Bu X, et al. Trends Mol Med. 2016 Jun;22(6):448-451. doi: 10.1016/j.molmed.2016.04.008. Epub 2016 May 9. Trends Mol Med. 2016. PMID: 27174038 Free PMC article.

6

Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance.

Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira NT, Tan Y, Ci Y, Wu F, Dai X, Guo J, Huang YH, Fan C, Ren S, Sun Y, Freeman GJ, Sicinski P, Wei W. Zhang J, et al. Among authors: bu x. Nature. 2018 Jan 4;553(7686):91-95. doi: 10.1038/nature25015. Epub 2017 Nov 16. Nature. 2018. PMID: 29160310 Free PMC article.

7

Immune Checkpoint Blockade in Breast Cancer Therapy.

Bu X, Yao Y, Li X. Bu X, et al. Adv Exp Med Biol. 2017;1026:383-402. doi: 10.1007/978-981-10-6020-5_18. Adv Exp Med Biol. 2017. PMID: 29282694 Review.

8

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response.

Jiang P, Gu S, Pan D, Fu J, Sahu A, Hu X, Li Z, Traugh N, Bu X, Li B, Liu J, Freeman GJ, Brown MA, Wucherpfennig KW, Liu XS. Jiang P, et al. Among authors: bu x. Nat Med. 2018 Oct;24(10):1550-1558. doi: 10.1038/s41591-018-0136-1. Epub 2018 Aug 20. Nat Med. 2018. PMID: 30127393 Free PMC article.

9

A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression.

Mahoney KM, Shukla SA, Patsoukis N, Chaudhri A, Browne EP, Arazi A, Eisenhaure TM, Pendergraft WF 3rd, Hua P, Pham HC, Bu X, Zhu B, Hacohen N, Fritsch EF, Boussiotis VA, Wu CJ, Freeman GJ. Mahoney KM, et al. Among authors: bu x. Cancer Immunol Immunother. 2019 Mar;68(3):421-432. doi: 10.1007/s00262-018-2282-1. Epub 2018 Dec 18. Cancer Immunol Immunother. 2019. PMID: 30564891 Free PMC article.

10

Author Correction: Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance.

Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira NT, Tan Y, Ci Y, Wu F, Dai X, Guo J, Huang YH, Fan C, Ren S, Sun Y, Freeman GJ, Sicinski P, Wei W. Zhang J, et al. Among authors: bu x. Nature. 2019 Jul;571(7766):E10. doi: 10.1038/s41586-019-1351-8. Nature. 2019. PMID: 31270456

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