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Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human.
Kolbe E, Aleithe S, Rennert C, Spormann L, Ott F, Meierhofer D, Gajowski R, Stöpel C, Hoehme S, Kücken M, Brusch L, Seifert M, von Schoenfels W, Schafmayer C, Brosch M, Hofmann U, Damm G, Seehofer D, Hampe J, Gebhardt R, Matz-Soja M. Kolbe E, et al. Among authors: brusch l. Cell Rep. 2019 Dec 24;29(13):4553-4567.e7. doi: 10.1016/j.celrep.2019.11.104. Cell Rep. 2019. PMID: 31875560 Free article.
Three-dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression.
Segovia-Miranda F, Morales-Navarrete H, Kücken M, Moser V, Seifert S, Repnik U, Rost F, Brosch M, Hendricks A, Hinz S, Röcken C, Lütjohann D, Kalaidzidis Y, Schafmayer C, Brusch L, Hampe J, Zerial M. Segovia-Miranda F, et al. Among authors: brusch l. Nat Med. 2019 Dec;25(12):1885-1893. doi: 10.1038/s41591-019-0660-7. Epub 2019 Dec 2. Nat Med. 2019. PMID: 31792455 Free PMC article.
Diploid hepatocytes drive physiological liver renewal in adult humans.
Heinke P, Rost F, Rode J, Trus P, Simonova I, Lázár E, Feddema J, Welsch T, Alkass K, Salehpour M, Zimmermann A, Seehofer D, Possnert G, Damm G, Druid H, Brusch L, Bergmann O. Heinke P, et al. Among authors: brusch l. Cell Syst. 2022 Jun 15;13(6):499-507.e12. doi: 10.1016/j.cels.2022.05.001. Epub 2022 May 31. Cell Syst. 2022. PMID: 35649419 Free article.
Apical bulkheads accumulate as adaptive response to impaired bile flow in liver disease.
Mayer C, Nehring S, Kücken M, Repnik U, Seifert S, Sljukic A, Delpierre J, Morales-Navarrete H, Hinz S, Brosch M, Chung B, Karlsen T, Huch M, Kalaidzidis Y, Brusch L, Hampe J, Schafmayer C, Zerial M. Mayer C, et al. Among authors: brusch l. EMBO Rep. 2023 Sep 6;24(9):e57181. doi: 10.15252/embr.202357181. Epub 2023 Jul 31. EMBO Rep. 2023. PMID: 37522754 Free PMC article.
Mathematical modeling of regenerative processes.
Chara O, Tanaka EM, Brusch L. Chara O, et al. Among authors: brusch l. Curr Top Dev Biol. 2014;108:283-317. doi: 10.1016/B978-0-12-391498-9.00011-5. Curr Top Dev Biol. 2014. PMID: 24512713 Review.
A Predictive 3D Multi-Scale Model of Biliary Fluid Dynamics in the Liver Lobule.
Meyer K, Ostrenko O, Bourantas G, Morales-Navarrete H, Porat-Shliom N, Segovia-Miranda F, Nonaka H, Ghaemi A, Verbavatz JM, Brusch L, Sbalzarini I, Kalaidzidis Y, Weigert R, Zerial M. Meyer K, et al. Among authors: brusch l. Cell Syst. 2017 Mar 22;4(3):277-290.e9. doi: 10.1016/j.cels.2017.02.008. Epub 2017 Mar 18. Cell Syst. 2017. PMID: 28330614 Free PMC article.
Liquid-crystal organization of liver tissue.
Morales-Navarrete H, Nonaka H, Scholich A, Segovia-Miranda F, de Back W, Meyer K, Bogorad RL, Koteliansky V, Brusch L, Kalaidzidis Y, Jülicher F, Friedrich BM, Zerial M. Morales-Navarrete H, et al. Among authors: brusch l. Elife. 2019 Jun 17;8:e44860. doi: 10.7554/eLife.44860. Elife. 2019. PMID: 31204997 Free PMC article.
49 results