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IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer.
Caronni N, La Terza F, Vittoria FM, Barbiera G, Mezzanzanica L, Cuzzola V, Barresi S, Pellegatta M, Canevazzi P, Dunsmore G, Leonardi C, Montaldo E, Lusito E, Dugnani E, Citro A, Ng MSF, Schiavo Lena M, Drago D, Andolfo A, Brugiapaglia S, Scagliotti A, Mortellaro A, Corbo V, Liu Z, Mondino A, Dellabona P, Piemonti L, Taveggia C, Doglioni C, Cappello P, Novelli F, Iannacone M, Ng LG, Ginhoux F, Crippa S, Falconi M, Bonini C, Naldini L, Genua M, Ostuni R. Caronni N, et al. Among authors: brugiapaglia s. Nature. 2023 Nov;623(7986):415-422. doi: 10.1038/s41586-023-06685-2. Epub 2023 Nov 1. Nature. 2023. PMID: 37914939 Free article.
Circulating autoantibodies to alpha-enolase (ENO1) and far upstream element-binding protein 1 (FUBP1) are negative prognostic factors for pancreatic cancer patient survival.
Curcio C, Rosso T, Brugiapaglia S, Guadagnin G, Giordano D, Castellino B, Satolli MA, Spadi R, Campra D, Moro F, Papotti MG, Bertero L, Cassoni P, De Angelis C, Langella S, Ferrero A, Armentano S, Bellotti G, Fenocchio E, Nuzzo A, Ciccone G, Novelli F. Curcio C, et al. Among authors: brugiapaglia s. Clin Exp Med. 2023 Dec;23(8):5089-5100. doi: 10.1007/s10238-023-01236-5. Epub 2023 Nov 1. Clin Exp Med. 2023. PMID: 37910256 Free PMC article.
HLA-DPB1*13:01 associates with enhanced, and KIR2DS4*001 with diminished protection from developing severe COVID-19.
Farias TDJ, Brugiapaglia S, Croci S, Magistroni P, Curcio C, Zguro K, Fallerini C, Fava F, Pettini F, Kichula KM, Pollock NR, Font-Porterias N, Palmer WH, Marin WM, Baldassarri M, Bruttini M, Hollenbach JA, Hendricks AE, Meloni I, Novelli F; GEN-COVID Multicenter Study Group; Renieri A, Furini S, Norman PJ, Amoroso A. Farias TDJ, et al. Among authors: brugiapaglia s. HLA. 2024 Jan;103(1):e15251. doi: 10.1111/tan.15251. Epub 2023 Oct 18. HLA. 2024. PMID: 37850268 Free article.
The dark side of immunotherapy: pancreatic cancer.
Mucciolo G, Roux C, Scagliotti A, Brugiapaglia S, Novelli F, Cappello P. Mucciolo G, et al. Among authors: brugiapaglia s. Cancer Drug Resist. 2020 May 11;3(3):491-520. doi: 10.20517/cdr.2020.13. eCollection 2020. Cancer Drug Resist. 2020. PMID: 35582441 Free PMC article. Review.