Brugghe HF - Search Results

1

Immunization with Small Amyloid-β-derived Cyclopeptide Conjugates Diminishes Amyloid-β-Induced Neurodegeneration in Mice.

Mulder CK, Dong Y, Brugghe HF, Timmermans HA, Tilstra W, Westdijk J, van Riet E, van Steeg H, Hoogerhout P, Eisel UL. Mulder CK, et al. Among authors: brugghe hf. J Alzheimers Dis. 2016;52(3):1111-23. doi: 10.3233/JAD-151136. J Alzheimers Dis. 2016. PMID: 27060957 Free PMC article.

2

A cyclic undecamer peptide mimics a turn in folded Alzheimer amyloid β and elicits antibodies against oligomeric and fibrillar amyloid and plaques.

Hoogerhout P, Kamphuis W, Brugghe HF, Sluijs JA, Timmermans HA, Westdijk J, Zomer G, Boog CJ, Hol EM, van den Dobbelsteen GP. Hoogerhout P, et al. Among authors: brugghe hf. PLoS One. 2011 Apr 19;6(4):e19110. doi: 10.1371/journal.pone.0019110. PLoS One. 2011. PMID: 21526148 Free PMC article.

3

Conjugates of synthetic cyclic peptides elicit bactericidal antibodies against a conformational epitope on a class 1 outer membrane protein of Neisseria meningitidis.

Hoogerhout P, Donders EM, van Gaans-van den Brink JA, Kuipers B, Brugghe HF, van Unen LM, Timmermans HA, ten Hove GJ, de Jong AP, Peeters CC, et al. Hoogerhout P, et al. Among authors: brugghe hf. Infect Immun. 1995 Sep;63(9):3473-8. doi: 10.1128/iai.63.9.3473-3478.1995. Infect Immun. 1995. PMID: 7543883 Free PMC article.

4

Identification of immunodominant epitopes derived from the respiratory syncytial virus fusion protein that are recognized by human CD4 T cells.

van Bleek GM, Poelen MC, van der Most R, Brugghe HF, Timmermans HA, Boog CJ, Hoogerhout P, Otten HG, van Els CA. van Bleek GM, et al. Among authors: brugghe hf. J Virol. 2003 Jan;77(2):980-8. doi: 10.1128/jvi.77.2.980-988.2003. J Virol. 2003. PMID: 12502814 Free PMC article.

5

Epitope specificity of murine and human bactericidal antibodies against PorA P1.7,16 induced with experimental meningococcal group B vaccines.

Rouppe van der Voort EM, Kuipers B, Brugghe HF, van Unen LM, Timmermans HA, Hoogerhout P, Poolman JT. Rouppe van der Voort EM, et al. Among authors: brugghe hf. FEMS Immunol Med Microbiol. 1997 Mar;17(3):139-48. doi: 10.1111/j.1574-695X.1997.tb01006.x. FEMS Immunol Med Microbiol. 1997. PMID: 9093834 Free article. Clinical Trial.

6

Identification of formaldehyde-induced modifications in proteins: reactions with model peptides.

Metz B, Kersten GF, Hoogerhout P, Brugghe HF, Timmermans HA, de Jong A, Meiring H, ten Hove J, Hennink WE, Crommelin DJ, Jiskoot W. Metz B, et al. Among authors: brugghe hf. J Biol Chem. 2004 Feb 20;279(8):6235-43. doi: 10.1074/jbc.M310752200. Epub 2003 Nov 24. J Biol Chem. 2004. PMID: 14638685 Free article.

7

Simultaneous multiple synthesis and selective conjugation of cyclized peptides derived from a surface loop of a meningococcal class 1 outer membrane protein.

Brugghe HF, Timmermans HA, Van Unen LM, Ten Hove GJ, Van de Werken G, Poolman JT, Hoogerhout P. Brugghe HF, et al. Int J Pept Protein Res. 1994 Feb;43(2):166-72. doi: 10.1111/j.1399-3011.1994.tb00518.x. Int J Pept Protein Res. 1994. PMID: 8200735

8

Immunogenicity of peptide-vaccine candidates predicted by molecular dynamics simulations.

Oomen CJ, Hoogerhout P, Bonvin AM, Kuipers B, Brugghe H, Timmermans H, Haseley SR, van Alphen L, Gros P. Oomen CJ, et al. J Mol Biol. 2003 May 16;328(5):1083-9. doi: 10.1016/s0022-2836(03)00377-2. J Mol Biol. 2003. PMID: 12729743

9

Mass tag-assisted identification of naturally processed HLA class II-presented meningococcal peptides recognized by CD4+ T lymphocytes.

Meiring HD, Kuipers B, van Gaans-van den Brink JA, Poelen MC, Timmermans H, Baart G, Brugghe H, van Schie J, Boog CJ, de Jong AP, van Els CA. Meiring HD, et al. J Immunol. 2005 May 1;174(9):5636-43. doi: 10.4049/jimmunol.174.9.5636. J Immunol. 2005. PMID: 15843563

10

T-cell responses to outer membrane proteins of Neisseria meningitidis: comparative study of the Opa, Opc, and PorA proteins.

Wiertz EJ, Delvig A, Donders EM, Brugghe HF, van Unen LM, Timmermans HA, Achtman M, Hoogerhout P, Poolman JT. Wiertz EJ, et al. Among authors: brugghe hf. Infect Immun. 1996 Jan;64(1):298-304. doi: 10.1128/iai.64.1.298-304.1996. Infect Immun. 1996. PMID: 8557355 Free PMC article.

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