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A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma: the Ipi-Glio trial protocol.
Brown NF, Ng SM, Brooks C, Coutts T, Holmes J, Roberts C, Elhussein L, Hoskin P, Maughan T, Blagden S, Mulholland P. Brown NF, et al. BMC Cancer. 2020 Mar 12;20(1):198. doi: 10.1186/s12885-020-6624-y. BMC Cancer. 2020. PMID: 32164579 Free PMC article. Clinical Trial.
Multi-Center Randomized Phase II Study Comparing Cediranib plus Gefitinib with Cediranib plus Placebo in Subjects with Recurrent/Progressive Glioblastoma.
Brown N, McBain C, Nash S, Hopkins K, Sanghera P, Saran F, Phillips M, Dungey F, Clifton-Hadley L, Wanek K, Krell D, Jeffries S, Khan I, Smith P, Mulholland P. Brown N, et al. PLoS One. 2016 May 27;11(5):e0156369. doi: 10.1371/journal.pone.0156369. eCollection 2016. PLoS One. 2016. PMID: 27232884 Free PMC article. Clinical Trial.
Dabrafenib and trametinib in BRAFV600E mutated glioma.
Brown NF, Carter T, Kitchen N, Mulholland P. Brown NF, et al. CNS Oncol. 2017 Oct;6(4):291-296. doi: 10.2217/cns-2017-0006. Epub 2017 Oct 6. CNS Oncol. 2017. PMID: 28984141 Free PMC article.
A study of the focal adhesion kinase inhibitor GSK2256098 in patients with recurrent glioblastoma with evaluation of tumor penetration of [11C]GSK2256098.
Brown NF, Williams M, Arkenau HT, Fleming RA, Tolson J, Yan L, Zhang J, Singh R, Auger KR, Lenox L, Cox D, Lewis Y, Plisson C, Searle G, Saleem A, Blagden S, Mulholland P. Brown NF, et al. Neuro Oncol. 2018 Nov 12;20(12):1634-1642. doi: 10.1093/neuonc/noy078. Neuro Oncol. 2018. PMID: 29788497 Free PMC article. Clinical Trial.
Harnessing the immune system in glioblastoma.
Brown NF, Carter TJ, Ottaviani D, Mulholland P. Brown NF, et al. Br J Cancer. 2018 Nov;119(10):1171-1181. doi: 10.1038/s41416-018-0258-8. Epub 2018 Nov 5. Br J Cancer. 2018. PMID: 30393372 Free PMC article. Review.
Survival Outcomes and Prognostic Factors in Glioblastoma.
Brown NF, Ottaviani D, Tazare J, Gregson J, Kitchen N, Brandner S, Fersht N, Mulholland P. Brown NF, et al. Cancers (Basel). 2022 Jun 28;14(13):3161. doi: 10.3390/cancers14133161. Cancers (Basel). 2022. PMID: 35804940 Free PMC article.
Phase 1/2a trial of intravenous BAL101553, a novel controller of the spindle assembly checkpoint, in advanced solid tumours.
Kristeleit R, Evans J, Molife LR, Tunariu N, Shaw H, Slater S, Haris NRM, Brown NF, Forster MD, Diamantis N, Rulach R, Greystoke A, Asghar U, Rata M, Anderson S, Bachmann F, Hannah A, Kaindl T, Lane HA, Larger PJ, Schmitt-Hoffmann A, Engelhardt M, Tzankov A, Plummer R, Lopez J. Kristeleit R, et al. Among authors: brown nf. Br J Cancer. 2020 Oct;123(9):1360-1369. doi: 10.1038/s41416-020-1010-8. Epub 2020 Aug 3. Br J Cancer. 2020. PMID: 32741975 Free PMC article. Clinical Trial.
91 results