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Universal immunity to influenza must outwit immune evasion.
Quiñones-Parra S, Loh L, Brown LE, Kedzierska K, Valkenburg SA. Quiñones-Parra S, et al. Among authors: brown le. Front Microbiol. 2014 Jun 12;5:285. doi: 10.3389/fmicb.2014.00285. eCollection 2014. Front Microbiol. 2014. PMID: 24971078 Free PMC article. Review.
Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients.
Nguyen THO, Koutsakos M, van de Sandt CE, Crawford JC, Loh L, Sant S, Grzelak L, Allen EK, Brahm T, Clemens EB, Auladell M, Hensen L, Wang Z, Nüssing S, Jia X, Günther P, Wheatley AK, Kent SJ, Aban M, Deng YM, Laurie KL, Hurt AC, Gras S, Rossjohn J, Crowe J, Xu J, Jackson D, Brown LE, La Gruta N, Chen W, Doherty PC, Turner SJ, Kotsimbos TC, Thomas PG, Cheng AC, Kedzierska K. Nguyen THO, et al. Among authors: brown le. Nat Commun. 2021 May 11;12(1):2691. doi: 10.1038/s41467-021-23018-x. Nat Commun. 2021. PMID: 33976217 Free PMC article.
Immune profiling of influenza-specific B- and T-cell responses in macaques using flow cytometry-based assays.
Koutsakos M, Sekiya T, Chua BY, Nguyen THO, Wheatley AK, Juno JA, Ohno M, Nomura N, Ohara Y, Nishimura T, Endo M, Suzuki S, Ishigaki H, Nakayama M, Nguyen CT, Itoh Y, Shingai M, Ogasawara K, Kino Y, Kent SJ, Jackson DC, Brown LE, Kida H, Kedzierska K. Koutsakos M, et al. Among authors: brown le. Immunol Cell Biol. 2021 Jan;99(1):97-106. doi: 10.1111/imcb.12383. Epub 2020 Sep 7. Immunol Cell Biol. 2021. PMID: 32741011
Live Attenuated Influenza Vaccines engineered to express the nucleoprotein of a recent isolate stimulate human influenza CD8+ T cells more relevant to current infections.
Korenkov D, Nguyen THO, Isakova-Sivak I, Smolonogina T, Brown LE, Kedzierska K, Rudenko L. Korenkov D, et al. Among authors: brown le. Hum Vaccin Immunother. 2018 Apr 3;14(4):941-946. doi: 10.1080/21645515.2017.1417713. Epub 2018 Jan 23. Hum Vaccin Immunother. 2018. PMID: 29252117 Free PMC article.
Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude.
Quinn KM, Kan WT, Watson KA, Liddicoat BJ, Swan NG, McQuilten H, Denton AE, Li J, Chen W, Brown LE, Jackson DC, Reading PC, Doherty PC, Kedzierska K, Kedzierski L, Turner SJ, La Gruta NL. Quinn KM, et al. Among authors: brown le. PLoS One. 2017 Sep 8;12(9):e0184732. doi: 10.1371/journal.pone.0184732. eCollection 2017. PLoS One. 2017. PMID: 28886201 Free PMC article.
534 results