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Sputum microbiome temporal variability and dysbiosis in chronic obstructive pulmonary disease exacerbations: an analysis of the COPDMAP study.
Wang Z, Singh R, Miller BE, Tal-Singer R, Van Horn S, Tomsho L, Mackay A, Allinson JP, Webb AJ, Brookes AJ, George LM, Barker B, Kolsum U, Donnelly LE, Belchamber K, Barnes PJ, Singh D, Brightling CE, Donaldson GC, Wedzicha JA, Brown JR; COPDMAP. Wang Z, et al. Among authors: brown jr. Thorax. 2018 Apr;73(4):331-338. doi: 10.1136/thoraxjnl-2017-210741. Epub 2017 Dec 21. Thorax. 2018. PMID: 29269441 Free article.
Inflammatory Endotype-associated Airway Microbiome in Chronic Obstructive Pulmonary Disease Clinical Stability and Exacerbations: A Multicohort Longitudinal Analysis.
Wang Z, Locantore N, Haldar K, Ramsheh MY, Beech AS, Ma W, Brown JR, Tal-Singer R, Barer MR, Bafadhel M, Donaldson GC, Wedzicha JA, Singh D, Wilkinson TMA, Miller BE, Brightling CE. Wang Z, et al. Among authors: brown jr. Am J Respir Crit Care Med. 2021 Jun 15;203(12):1488-1502. doi: 10.1164/rccm.202009-3448OC. Am J Respir Crit Care Med. 2021. PMID: 33332995 Free PMC article.
Lung microbiome dynamics in COPD exacerbations.
Wang Z, Bafadhel M, Haldar K, Spivak A, Mayhew D, Miller BE, Tal-Singer R, Johnston SL, Ramsheh MY, Barer MR, Brightling CE, Brown JR. Wang Z, et al. Among authors: brown jr. Eur Respir J. 2016 Apr;47(4):1082-92. doi: 10.1183/13993003.01406-2015. Epub 2016 Feb 25. Eur Respir J. 2016. PMID: 26917613 Free article.
The sputum microbiome is distinct between COPD and health, independent of smoking history.
Haldar K, George L, Wang Z, Mistry V, Ramsheh MY, Free RC, John C, Reeve NF, Miller BE, Tal-Singer R, Webb AJ, Brookes AJ, Tobin MD, Singh D, Donaldson GC, Wedzicha JA, Brown JR, Barer MR, Brightling CE. Haldar K, et al. Among authors: brown jr. Respir Res. 2020 Jul 14;21(1):183. doi: 10.1186/s12931-020-01448-3. Respir Res. 2020. PMID: 32664956 Free PMC article.
Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations.
Mayhew D, Devos N, Lambert C, Brown JR, Clarke SC, Kim VL, Magid-Slav M, Miller BE, Ostridge KK, Patel R, Sathe G, Simola DF, Staples KJ, Sung R, Tal-Singer R, Tuck AC, Van Horn S, Weynants V, Williams NP, Devaster JM, Wilkinson TMA; AERIS Study Group. Mayhew D, et al. Among authors: brown jr. Thorax. 2018 May;73(5):422-430. doi: 10.1136/thoraxjnl-2017-210408. Epub 2018 Jan 31. Thorax. 2018. PMID: 29386298 Free PMC article.
T Cell- and Monocyte-Specific RNA-Sequencing Analysis in Septic and Nonseptic Critically Ill Patients and in Patients with Cancer.
Washburn ML, Wang Z, Walton AH, Goedegebuure SP, Figueroa DJ, Van Horn S, Grossman J, Remlinger K, Madsen H, Brown J, Srinivasan R, Wolf AI, Berger SB, Yi VN, Hawkins WG, Fields RC, Hotchkiss RS. Washburn ML, et al. J Immunol. 2019 Oct 1;203(7):1897-1908. doi: 10.4049/jimmunol.1900560. Epub 2019 Sep 4. J Immunol. 2019. PMID: 31484735 Free PMC article. Clinical Trial.
3,837 results