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Protein imbalance in the development of skeletal muscle wasting in tumour-bearing mice.
Brown JL, Lee DE, Rosa-Caldwell ME, Brown LA, Perry RA, Haynie WS, Huseman K, Sataranatarajan K, Van Remmen H, Washington TA, Wiggs MP, Greene NP. Brown JL, et al. Among authors: brown la. J Cachexia Sarcopenia Muscle. 2018 Oct;9(5):987-1002. doi: 10.1002/jcsm.12354. Epub 2018 Oct 16. J Cachexia Sarcopenia Muscle. 2018. PMID: 30328290 Free PMC article.
Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia.
Sataranatarajan K, Pharaoh G, Brown JL, Ranjit R, Piekarz KM, Street K, Wren JD, Georgescu C, Kinter C, Kinter M, Freeman WM, Richardson A, Van Remmen H. Sataranatarajan K, et al. Among authors: brown jl. Geroscience. 2020 Aug;42(4):1101-1118. doi: 10.1007/s11357-020-00189-x. Epub 2020 May 12. Geroscience. 2020. PMID: 32394347 Free PMC article.
Targeting cPLA2 derived lipid hydroperoxides as a potential intervention for sarcopenia.
Pharaoh G, Brown JL, Sataranatarajan K, Kneis P, Bian J, Ranjit R, Hadad N, Georgescu C, Rabinovitch P, Ran Q, Wren JD, Freeman W, Kinter M, Richardson A, Van Remmen H. Pharaoh G, et al. Among authors: brown jl. Sci Rep. 2020 Aug 18;10(1):13968. doi: 10.1038/s41598-020-70792-7. Sci Rep. 2020. PMID: 32811851 Free PMC article.
Neuron-specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice.
Bhaskaran S, Pollock N, C Macpherson P, Ahn B, Piekarz KM, Staunton CA, Brown JL, Qaisar R, Vasilaki A, Richardson A, McArdle A, Jackson MJ, Brooks SV, Van Remmen H. Bhaskaran S, et al. Among authors: brown jl. Aging Cell. 2020 Oct;19(10):e13225. doi: 10.1111/acel.13225. Epub 2020 Sep 4. Aging Cell. 2020. PMID: 32886862 Free PMC article.
Cancer cachexia in a mouse model of oxidative stress.
Brown JL, Lawrence MM, Ahn B, Kneis P, Piekarz KM, Qaisar R, Ranjit R, Bian J, Pharaoh G, Brown C, Peelor FF 3rd, Kinter MT, Miller BF, Richardson A, Van Remmen H. Brown JL, et al. Among authors: brown c. J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1688-1704. doi: 10.1002/jcsm.12615. Epub 2020 Sep 12. J Cachexia Sarcopenia Muscle. 2020. PMID: 32918528 Free PMC article.
Senolytic treatment reduces cell senescence and necroptosis in Sod1 knockout mice that is associated with reduced inflammation and hepatocellular carcinoma.
Thadathil N, Selvarani R, Mohammed S, Nicklas EH, Tran AL, Kamal M, Luo W, Brown JL, Lawrence MM, Borowik AK, Miller BF, Van Remmen H, Richardson A, Deepa SS. Thadathil N, et al. Among authors: brown jl. Aging Cell. 2022 Aug;21(8):e13676. doi: 10.1111/acel.13676. Epub 2022 Jul 23. Aging Cell. 2022. PMID: 35869934 Free PMC article.
Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis.
Bhaskaran S, Kumar G, Thadathil N, Piekarz KM, Mohammed S, Lopez SD, Qaisar R, Walton D, Brown JL, Murphy A, Smith N, Saunders D, Beckstead MJ, Plafker S, Lewis TL Jr, Towner R, Deepa SS, Richardson A, Axtell RC, Van Remmen H. Bhaskaran S, et al. Among authors: brown jl. Redox Biol. 2023 Feb;59:102550. doi: 10.1016/j.redox.2022.102550. Epub 2022 Nov 26. Redox Biol. 2023. PMID: 36470129 Free PMC article.
1,015 results