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A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine.
Sebastian C, Ferrer C, Serra M, Choi JE, Ducano N, Mira A, Shah MS, Stopka SA, Perciaccante AJ, Isella C, Moya-Rull D, Vara-Messler M, Giordano S, Maldi E, Desai N, Capen DE, Medico E, Cetinbas M, Sadreyev RI, Brown D, Rivera MN, Sapino A, Breault DT, Agar NYR, Mostoslavsky R. Sebastian C, et al. Among authors: brown d. Nat Commun. 2022 Mar 21;13(1):1503. doi: 10.1038/s41467-022-29085-y. Nat Commun. 2022. PMID: 35314684 Free PMC article.
Macrophages Facilitate Electrical Conduction in the Heart.
Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Seidman JG, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M. Hulsmans M, et al. Among authors: brown d. Cell. 2017 Apr 20;169(3):510-522.e20. doi: 10.1016/j.cell.2017.03.050. Cell. 2017. PMID: 28431249 Free PMC article.
Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion.
Zaidman NA, Tomilin VN, Hassanzadeh Khayyat N, Damarla M, Tidmore J, Capen DE, Brown D, Pochynyuk OM, Pluznick JL. Zaidman NA, et al. Among authors: brown d. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26470-26481. doi: 10.1073/pnas.2007620117. Epub 2020 Oct 1. Proc Natl Acad Sci U S A. 2020. PMID: 33004624 Free PMC article.
B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis.
Schloss MJ, Hulsmans M, Rohde D, Lee IH, Severe N, Foy BH, Pulous FE, Zhang S, Kokkaliaris KD, Frodermann V, Courties G, Yang C, Iwamoto Y, Knudsen AS, McAlpine CS, Yamazoe M, Schmidt SP, Wojtkiewicz GR, Masson GS, Gustafsson K, Capen D, Brown D, Higgins JM, Scadden DT, Libby P, Swirski FK, Naxerova K, Nahrendorf M. Schloss MJ, et al. Among authors: brown d. Nat Immunol. 2022 Apr;23(4):605-618. doi: 10.1038/s41590-022-01165-7. Epub 2022 Mar 28. Nat Immunol. 2022. PMID: 35352063 Free PMC article.
Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis.
Pulous FE, Cruz-Hernández JC, Yang C, Kaya Ζ, Paccalet A, Wojtkiewicz G, Capen D, Brown D, Wu JW, Schloss MJ, Vinegoni C, Richter D, Yamazoe M, Hulsmans M, Momin N, Grune J, Rohde D, McAlpine CS, Panizzi P, Weissleder R, Kim DE, Swirski FK, Lin CP, Moskowitz MA, Nahrendorf M. Pulous FE, et al. Among authors: brown d. Nat Neurosci. 2022 May;25(5):567-576. doi: 10.1038/s41593-022-01060-2. Epub 2022 May 2. Nat Neurosci. 2022. PMID: 35501382 Free PMC article.
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