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Reversal of epigenetic aging and immunosenescent trends in humans.
Fahy GM, Brooke RT, Watson JP, Good Z, Vasanawala SS, Maecker H, Leipold MD, Lin DTS, Kobor MS, Horvath S. Fahy GM, et al. Among authors: brooke rt. Aging Cell. 2019 Dec;18(6):e13028. doi: 10.1111/acel.13028. Epub 2019 Sep 8. Aging Cell. 2019. PMID: 31496122 Free PMC article.
Reversing immunosenescence for prevention of COVID-19.
Brooke RT, Fahy GM. Brooke RT, et al. Aging (Albany NY). 2020 Jun 28;12(12):11161-11162. doi: 10.18632/aging.103636. Epub 2020 Jun 28. Aging (Albany NY). 2020. PMID: 32597792 Free PMC article. No abstract available.
DNA methylation clocks for dogs and humans.
Horvath S, Lu AT, Haghani A, Zoller JA, Li CZ, Lim AR, Brooke RT, Raj K, Serres-Armero A, Dreger DL, Hogan AN, Plassais J, Ostrander EA. Horvath S, et al. Among authors: brooke rt. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2120887119. doi: 10.1073/pnas.2120887119. Epub 2022 May 17. Proc Natl Acad Sci U S A. 2022. PMID: 35580182 Free PMC article.
Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice.
Sanz-Ros J, Romero-García N, Mas-Bargues C, Monleón D, Gordevicius J, Brooke RT, Dromant M, Díaz A, Derevyanko A, Guío-Carrión A, Román-Domínguez A, Inglés M, Blasco MA, Horvath S, Viña J, Borrás C. Sanz-Ros J, et al. Among authors: brooke rt. Sci Adv. 2022 Oct 21;8(42):eabq2226. doi: 10.1126/sciadv.abq2226. Epub 2022 Oct 19. Sci Adv. 2022. PMID: 36260670 Free PMC article.
DNA methylation networks underlying mammalian traits.
Haghani A, Li CZ, Robeck TR, Zhang J, Lu AT, Ablaeva J, Acosta-Rodríguez VA, Adams DM, Alagaili AN, Almunia J, Aloysius A, Amor NMS, Ardehali R, Arneson A, Baker CS, Banks G, Belov K, Bennett NC, Black P, Blumstein DT, Bors EK, Breeze CE, Brooke RT, Brown JL, Carter G, Caulton A, Cavin JM, Chakrabarti L, Chatzistamou I, Chavez AS, Chen H, Cheng K, Chiavellini P, Choi OW, Clarke S, Cook JA, Cooper LN, Cossette ML, Day J, DeYoung J, Dirocco S, Dold C, Dunnum JL, Ehmke EE, Emmons CK, Emmrich S, Erbay E, Erlacher-Reid C, Faulkes CG, Fei Z, Ferguson SH, Finno CJ, Flower JE, Gaillard JM, Garde E, Gerber L, Gladyshev VN, Goya RG, Grant MJ, Green CB, Hanson MB, Hart DW, Haulena M, Herrick K, Hogan AN, Hogg CJ, Hore TA, Huang T, Izpisua Belmonte JC, Jasinska AJ, Jones G, Jourdain E, Kashpur O, Katcher H, Katsumata E, Kaza V, Kiaris H, Kobor MS, Kordowitzki P, Koski WR, Krützen M, Kwon SB, Larison B, Lee SG, Lehmann M, Lemaître JF, Levine AJ, Li X, Li C, Lim AR, Lin DTS, Lindemann DM, Liphardt SW, Little TJ, Macoretta N, Maddox D, Matkin CO, Mattison JA, McClure M, Mergl J, Meudt JJ, Montano GA, Mozhui K, Munshi-South J, Murphy WJ, Naderi A, Nagy M, Narayan P, Nathanielsz PW, Nguyen … See abstract for full author list ➔ Haghani A, et al. Among authors: brooke rt. Science. 2023 Aug 11;381(6658):eabq5693. doi: 10.1126/science.abq5693. Epub 2023 Aug 11. Science. 2023. PMID: 37561875
22 results