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iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome.
Landucci E, Brindisi M, Bianciardi L, Catania LM, Daga S, Croci S, Frullanti E, Fallerini C, Butini S, Brogi S, Furini S, Melani R, Molinaro A, Lorenzetti FC, Imperatore V, Amabile S, Mariani J, Mari F, Ariani F, Pizzorusso T, Pinto AM, Vaccarino FM, Renieri A, Campiani G, Meloni I. Landucci E, et al. Among authors: brogi s. Exp Cell Res. 2018 Jul 15;368(2):225-235. doi: 10.1016/j.yexcr.2018.05.001. Epub 2018 May 4. Exp Cell Res. 2018. PMID: 29730163 Free PMC article.
Resveratrol-like Compounds as SIRT1 Activators.
Ciccone L, Piragine E, Brogi S, Camodeca C, Fucci R, Calderone V, Nencetti S, Martelli A, Orlandini E. Ciccone L, et al. Among authors: brogi s. Int J Mol Sci. 2022 Dec 1;23(23):15105. doi: 10.3390/ijms232315105. Int J Mol Sci. 2022. PMID: 36499460 Free PMC article.
New Visions on Natural Products and Cancer Therapy: Autophagy and Related Regulatory Pathways.
Martelli A, Omrani M, Zarghooni M, Citi V, Brogi S, Calderone V, Sureda A, Lorzadeh S, da Silva Rosa SC, Grabarek BO, Staszkiewicz R, Los MJ, Nabavi SF, Nabavi SM, Mehrbod P, Klionsky DJ, Ghavami S. Martelli A, et al. Among authors: brogi s. Cancers (Basel). 2022 Nov 26;14(23):5839. doi: 10.3390/cancers14235839. Cancers (Basel). 2022. PMID: 36497321 Free PMC article. Review.
Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents.
Al-Sanea MM, Hamdi A, Brogi S, S Tawfik S, Othman DIA, Elshal M, Ur Rahman H, Parambi DGT, M Elbargisy R, Selim S, Mostafa EM, Mohamed AAB. Al-Sanea MM, et al. Among authors: s tawfik s, brogi s. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2162511. doi: 10.1080/14756366.2022.2162511. J Enzyme Inhib Med Chem. 2023. PMID: 36633257 Free PMC article.
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: further structure-activity relationships, in vivo studies, and preliminary toxicity profiling.
Gemma S, Camodeca C, Sanna Coccone S, Joshi BP, Bernetti M, Moretti V, Brogi S, Bonache de Marcos MC, Savini L, Taramelli D, Basilico N, Parapini S, Rottmann M, Brun R, Lamponi S, Caccia S, Guiso G, Summers RL, Martin RE, Saponara S, Gorelli B, Novellino E, Campiani G, Butini S. Gemma S, et al. Among authors: brogi s. J Med Chem. 2012 Aug 9;55(15):6948-67. doi: 10.1021/jm300802s. Epub 2012 Jul 27. J Med Chem. 2012. PMID: 22783984
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1.
Gemma S, Giovani S, Brindisi M, Tripaldi P, Brogi S, Savini L, Fiorini I, Novellino E, Butini S, Campiani G, Penzo M, Blackman MJ. Gemma S, et al. Among authors: brogi s. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5317-21. doi: 10.1016/j.bmcl.2012.06.023. Epub 2012 Jun 23. Bioorg Med Chem Lett. 2012. PMID: 22796182
Mimicking the intramolecular hydrogen bond: synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents.
Gemma S, Camodeca C, Brindisi M, Brogi S, Kukreja G, Kunjir S, Gabellieri E, Lucantoni L, Habluetzel A, Taramelli D, Basilico N, Gualdani R, Tadini-Buoninsegni F, Bartolommei G, Moncelli MR, Martin RE, Summers RL, Lamponi S, Savini L, Fiorini I, Valoti M, Novellino E, Campiani G, Butini S. Gemma S, et al. Among authors: brogi s. J Med Chem. 2012 Dec 13;55(23):10387-404. doi: 10.1021/jm300831b. Epub 2012 Nov 21. J Med Chem. 2012. PMID: 23145816
132 results