Brockmeier U - Search Results

1

BAG3 Overexpression Attenuates Ischemic Stroke Injury by Activating Autophagy and Inhibiting Apoptosis.

Liu X, Ye Q, Huang Z, Li X, Zhang L, Liu X, Wu YC, Brockmeier U, Hermann DM, Wang YC, Ren L. Liu X, et al. Among authors: brockmeier u. Stroke. 2023 Aug;54(8):2114-2125. doi: 10.1161/STROKEAHA.123.041783. Epub 2023 Jun 28. Stroke. 2023. PMID: 37377010

2

Neurotoxicity of ischemic astrocytes involves STAT3-mediated metabolic switching and depends on glycogen usage.

Borbor M, Yin D, Brockmeier U, Wang C, Doeckel M, Pillath-Eilers M, Kaltwasser B, Hermann DM, Dzyubenko E. Borbor M, et al. Among authors: brockmeier u. Glia. 2023 Jun;71(6):1553-1569. doi: 10.1002/glia.24357. Epub 2023 Feb 22. Glia. 2023. PMID: 36810803

3

Long-term treatment with chloroquine increases lifespan in middle-aged male mice possibly via autophagy modulation, proteasome inhibition and glycogen metabolism.

Doeppner TR, Coman C, Burdusel D, Ancuta DL, Brockmeier U, Pirici DN, Yaoyun K, Hermann DM, Popa-Wagner A. Doeppner TR, et al. Among authors: brockmeier u. Aging (Albany NY). 2022 May 23;14(10):4195-4210. doi: 10.18632/aging.204069. Epub 2022 May 23. Aging (Albany NY). 2022. PMID: 35609021 Free PMC article.

4

In oxygen-deprived tumor cells ERp57 provides radioprotection and ensures proliferation via c-Myc, PLK1 and the AKT pathway.

Ocklenburg T, Neumann F, Wolf A, Vogel J, Göpelt K, Baumann M, Baumann J, Kranz P, Metzen E, Brockmeier U. Ocklenburg T, et al. Among authors: brockmeier u. Sci Rep. 2021 Mar 30;11(1):7199. doi: 10.1038/s41598-021-86658-5. Sci Rep. 2021. PMID: 33785835 Free PMC article.

5

Overcoming hypoxia-induced resistance of pancreatic and lung tumor cells by disrupting the PERK-NRF2-HIF-axis.

Küper A, Baumann J, Göpelt K, Baumann M, Sänger C, Metzen E, Kranz P, Brockmeier U. Küper A, et al. Among authors: brockmeier u. Cell Death Dis. 2021 Jan 13;12(1):82. doi: 10.1038/s41419-020-03319-7. Cell Death Dis. 2021. PMID: 33441543 Free PMC article.

6

Tumor cells rely on the thiol oxidoreductase PDI for PERK signaling in order to survive ER stress.

Kranz P, Sänger C, Wolf A, Baumann J, Metzen E, Baumann M, Göpelt K, Brockmeier U. Kranz P, et al. Among authors: brockmeier u. Sci Rep. 2020 Sep 17;10(1):15299. doi: 10.1038/s41598-020-72259-1. Sci Rep. 2020. PMID: 32943707 Free PMC article.

7

Carotid body type I cells engage flavoprotein and Pin1 for oxygen sensing.

Bernardini A, Wolf A, Brockmeier U, Riffkin H, Metzen E, Acker-Palmer A, Fandrey J, Acker H. Bernardini A, et al. Among authors: brockmeier u. Am J Physiol Cell Physiol. 2020 Apr 1;318(4):C719-C731. doi: 10.1152/ajpcell.00320.2019. Epub 2020 Jan 22. Am J Physiol Cell Physiol. 2020. PMID: 31967857 Free article.

8

The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia.

Pompsch M, Vogel J, Classen F, Kranz P, Iliakis G, Riffkin H, Brockmeier U, Metzen E. Pompsch M, et al. Among authors: brockmeier u. BMC Cancer. 2018 Nov 29;18(1):1190. doi: 10.1186/s12885-018-5095-x. BMC Cancer. 2018. PMID: 30497423 Free PMC article.

9

Autophagy induced by ionizing radiation promotes cell death over survival in human colorectal cancer cells.

Classen F, Kranz P, Riffkin H, Pompsch M, Wolf A, Göpelt K, Baumann M, Baumann J, Brockmeier U, Metzen E. Classen F, et al. Among authors: brockmeier u. Exp Cell Res. 2019 Jan 1;374(1):29-37. doi: 10.1016/j.yexcr.2018.11.004. Epub 2018 Nov 6. Exp Cell Res. 2019. PMID: 30412717 Free article.

10

PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR).

Kranz P, Neumann F, Wolf A, Classen F, Pompsch M, Ocklenburg T, Baumann J, Janke K, Baumann M, Goepelt K, Riffkin H, Metzen E, Brockmeier U. Kranz P, et al. Among authors: brockmeier u. Cell Death Dis. 2017 Aug 10;8(8):e2986. doi: 10.1038/cddis.2017.369. Cell Death Dis. 2017. PMID: 28796255 Free PMC article.

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