Brock R - Search Results

1

The effect of subcellular localization on the efficiency of EGFR-targeted VHH photosensitizer conjugates.

van Lith SAM, van den Brand D, Wallbrecher R, Wübbeke L, van Duijnhoven SMJ, Mäkinen PI, Hoogstad-van Evert JS, Massuger L, Ylä-Herttuala S, Brock R, Leenders WPJ. van Lith SAM, et al. Among authors: brock r. Eur J Pharm Biopharm. 2018 Mar;124:63-72. doi: 10.1016/j.ejpb.2017.12.009. Epub 2017 Dec 20. Eur J Pharm Biopharm. 2018. PMID: 29274374 Free article.

2

Cell surface clustering of heparan sulfate proteoglycans by amphipathic cell-penetrating peptides does not contribute to uptake.

Verdurmen WP, Wallbrecher R, Schmidt S, Eilander J, Bovee-Geurts P, Fanghänel S, Bürck J, Wadhwani P, Ulrich AS, Brock R. Verdurmen WP, et al. Among authors: brock r. J Control Release. 2013 Aug 28;170(1):83-91. doi: 10.1016/j.jconrel.2013.05.001. Epub 2013 May 10. J Control Release. 2013. PMID: 23669260

3

Activation of cell-penetrating peptides by disulfide bridge formation of truncated precursors.

Bode SA, Wallbrecher R, Brock R, van Hest JC, Löwik DW. Bode SA, et al. Among authors: brock r. Chem Commun (Camb). 2014 Jan 14;50(4):415-7. doi: 10.1039/c3cc46826g. Chem Commun (Camb). 2014. PMID: 24247922

4

The stoichiometry of peptide-heparan sulfate binding as a determinant of uptake efficiency of cell-penetrating peptides.

Wallbrecher R, Verdurmen WP, Schmidt S, Bovee-Geurts PH, Broecker F, Reinhardt A, van Kuppevelt TH, Seeberger PH, Brock R. Wallbrecher R, et al. Among authors: brock r. Cell Mol Life Sci. 2014 Jul;71(14):2717-29. doi: 10.1007/s00018-013-1517-8. Epub 2013 Nov 24. Cell Mol Life Sci. 2014. PMID: 24270856

5

Glycosaminoglycans in the cellular uptake of drug delivery vectors - bystanders or active players?

Favretto ME, Wallbrecher R, Schmidt S, van de Putte R, Brock R. Favretto ME, et al. Among authors: brock r. J Control Release. 2014 Apr 28;180:81-90. doi: 10.1016/j.jconrel.2014.02.011. Epub 2014 Feb 16. J Control Release. 2014. PMID: 24548480 Review.

6

Exploration of the design principles of a cell-penetrating bicylic peptide scaffold.

Wallbrecher R, Depré L, Verdurmen WP, Bovée-Geurts PH, van Duinkerken RH, Zekveld MJ, Timmerman P, Brock R. Wallbrecher R, et al. Among authors: brock r. Bioconjug Chem. 2014 May 21;25(5):955-64. doi: 10.1021/bc500107f. Epub 2014 Apr 16. Bioconjug Chem. 2014. PMID: 24697151

7

Multivalent presentation of the cell-penetrating peptide nona-arginine on a linear scaffold strongly increases its membrane-perturbing capacity.

Chakrabarti A, Witsenburg JJ, Sinzinger MD, Richter M, Wallbrecher R, Cluitmans JC, Verdurmen WP, Tanis S, Adjobo-Hermans MJ, Rademann J, Brock R. Chakrabarti A, et al. Among authors: brock r. Biochim Biophys Acta. 2014 Dec;1838(12):3097-106. doi: 10.1016/j.bbamem.2014.08.001. Epub 2014 Aug 7. Biochim Biophys Acta. 2014. PMID: 25109936 Free article.

8

Methods to Study the Role of the Glycocalyx in the Uptake of Cell-Penetrating Peptides.

Schmidt S, Wallbrecher R, van Kuppevelt TH, Brock R. Schmidt S, et al. Among authors: brock r. Methods Mol Biol. 2015;1324:123-31. doi: 10.1007/978-1-4939-2806-4_8. Methods Mol Biol. 2015. PMID: 26202266

9

ERRATUM TO: Methods to Study the Role of the Glycocalyx in the Uptake of Cell-Penetrating Peptides.

Schmidt S, Wallbrecher R, van Kuppevelt TH, Brock R. Schmidt S, et al. Among authors: brock r. Methods Mol Biol. 2015;1324:E1. doi: 10.1007/978-1-4939-2806-4_32. Methods Mol Biol. 2015. PMID: 26510654 No abstract available.

10

Detecting Cytosolic Peptide Delivery with the GFP Complementation Assay in the Low Micromolar Range.

Schmidt S, Adjobo-Hermans MJ, Wallbrecher R, Verdurmen WP, Bovée-Geurts PH, van Oostrum J, Milletti F, Enderle T, Brock R. Schmidt S, et al. Among authors: brock r. Angew Chem Int Ed Engl. 2015 Dec 7;54(50):15105-8. doi: 10.1002/anie.201505913. Epub 2015 Oct 30. Angew Chem Int Ed Engl. 2015. PMID: 26515694

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