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CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.
Ricciardi S, Ungaro F, Hambrock M, Rademacher N, Stefanelli G, Brambilla D, Sessa A, Magagnotti C, Bachi A, Giarda E, Verpelli C, Kilstrup-Nielsen C, Sala C, Kalscheuer VM, Broccoli V. Ricciardi S, et al. Among authors: broccoli v. Nat Cell Biol. 2012 Sep;14(9):911-23. doi: 10.1038/ncb2566. Epub 2012 Aug 26. Nat Cell Biol. 2012. PMID: 22922712 Free PMC article.
Zrf1 is required to establish and maintain neural progenitor identity.
Aloia L, Di Stefano B, Sessa A, Morey L, Santanach A, Gutierrez A, Cozzuto L, Benitah SA, Graf T, Broccoli V, Di Croce L. Aloia L, et al. Among authors: broccoli v. Genes Dev. 2014 Jan 15;28(2):182-97. doi: 10.1101/gad.228510.113. Genes Dev. 2014. PMID: 24449271 Free PMC article.
153 results