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Critical considerations for the development of potency tests for therapeutic applications of mesenchymal stromal cell-derived small extracellular vesicles.
Gimona M, Brizzi MF, Choo ABH, Dominici M, Davidson SM, Grillari J, Hermann DM, Hill AF, de Kleijn D, Lai RC, Lai CP, Lim R, Monguió-Tortajada M, Muraca M, Ochiya T, Ortiz LA, Toh WS, Yi YW, Witwer KW, Giebel B, Lim SK. Gimona M, et al. Among authors: brizzi mf. Cytotherapy. 2021 May;23(5):373-380. doi: 10.1016/j.jcyt.2021.01.001. Epub 2021 Apr 10. Cytotherapy. 2021. PMID: 33934807
Obesity reduces the pro-angiogenic potential of adipose tissue stem cell-derived extracellular vesicles (EVs) by impairing miR-126 content: impact on clinical applications.
Togliatto G, Dentelli P, Gili M, Gallo S, Deregibus C, Biglieri E, Iavello A, Santini E, Rossi C, Solini A, Camussi G, Brizzi MF. Togliatto G, et al. Among authors: brizzi mf. Int J Obes (Lond). 2016 Jan;40(1):102-11. doi: 10.1038/ijo.2015.123. Epub 2015 Jun 30. Int J Obes (Lond). 2016. PMID: 26122028 Free PMC article.
Stem Cell-Derived, microRNA-Carrying Extracellular Vesicles: A Novel Approach to Interfering with Mesangial Cell Collagen Production in a Hyperglycaemic Setting.
Gallo S, Gili M, Lombardo G, Rossetti A, Rosso A, Dentelli P, Togliatto G, Deregibus MC, Taverna D, Camussi G, Brizzi MF. Gallo S, et al. Among authors: brizzi mf. PLoS One. 2016 Sep 9;11(9):e0162417. doi: 10.1371/journal.pone.0162417. eCollection 2016. PLoS One. 2016. PMID: 27611075 Free PMC article.
Extracellular vesicles as new players in angiogenesis.
Kholia S, Ranghino A, Garnieri P, Lopatina T, Deregibus MC, Rispoli P, Brizzi MF, Camussi G. Kholia S, et al. Among authors: brizzi mf. Vascul Pharmacol. 2016 Nov;86:64-70. doi: 10.1016/j.vph.2016.03.005. Epub 2016 Mar 22. Vascul Pharmacol. 2016. PMID: 27013016 Free article. Review.
Differential Therapeutic Effect of Extracellular Vesicles Derived by Bone Marrow and Adipose Mesenchymal Stem Cells on Wound Healing of Diabetic Ulcers and Correlation to Their Cargoes.
Pomatto M, Gai C, Negro F, Cedrino M, Grange C, Ceccotti E, Togliatto G, Collino F, Tapparo M, Figliolini F, Lopatina T, Brizzi MF, Camussi G. Pomatto M, et al. Among authors: brizzi mf. Int J Mol Sci. 2021 Apr 8;22(8):3851. doi: 10.3390/ijms22083851. Int J Mol Sci. 2021. PMID: 33917759 Free PMC article.
Extracellular vesicles from patients with Acute Coronary Syndrome impact on ischemia-reperfusion injury.
D'Ascenzo F, Femminò S, Ravera F, Angelini F, Caccioppo A, Franchin L, Grosso A, Comità S, Cavallari C, Penna C, De Ferrari GM, Camussi G, Pagliaro P, Brizzi MF. D'Ascenzo F, et al. Among authors: brizzi mf. Pharmacol Res. 2021 Aug;170:105715. doi: 10.1016/j.phrs.2021.105715. Epub 2021 Jun 7. Pharmacol Res. 2021. PMID: 34111564 Free article. Clinical Trial.
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