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TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways.
Wang S, Sudan R, Peng V, Zhou Y, Du S, Yuede CM, Lei T, Hou J, Cai Z, Cella M, Nguyen K, Poliani PL, Beatty WL, Chen Y, Cao S, Lin K, Rodrigues C, Ellebedy AH, Gilfillan S, Brown GD, Holtzman DM, Brioschi S, Colonna M. Wang S, et al. Among authors: brioschi s. Cell. 2022 Oct 27;185(22):4153-4169.e19. doi: 10.1016/j.cell.2022.09.033. Cell. 2022. PMID: 36306735 Free PMC article.
The CNS Immune-Privilege Goes Down the Drain(age).
Brioschi S, Colonna M. Brioschi S, et al. Trends Pharmacol Sci. 2019 Jan;40(1):1-3. doi: 10.1016/j.tips.2018.11.006. Epub 2018 Dec 5. Trends Pharmacol Sci. 2019. PMID: 30528463
Fifty Shades of Microglia.
Brioschi S, Peng V, Colonna M. Brioschi S, et al. Trends Neurosci. 2019 Jul;42(7):440-443. doi: 10.1016/j.tins.2019.03.010. Epub 2019 Apr 18. Trends Neurosci. 2019. PMID: 31005331
TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy.
Molgora M, Esaulova E, Vermi W, Hou J, Chen Y, Luo J, Brioschi S, Bugatti M, Omodei AS, Ricci B, Fronick C, Panda SK, Takeuchi Y, Gubin MM, Faccio R, Cella M, Gilfillan S, Unanue ER, Artyomov MN, Schreiber RD, Colonna M. Molgora M, et al. Among authors: brioschi s. Cell. 2020 Aug 20;182(4):886-900.e17. doi: 10.1016/j.cell.2020.07.013. Epub 2020 Aug 11. Cell. 2020. PMID: 32783918 Free PMC article.
Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease.
Ellwanger DC, Wang S, Brioschi S, Shao Z, Green L, Case R, Yoo D, Weishuhn D, Rathanaswami P, Bradley J, Rao S, Cha D, Luan P, Sambashivan S, Gilfillan S, Hasson SA, Foltz IN, van Lookeren Campagne M, Colonna M. Ellwanger DC, et al. Among authors: brioschi s. Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2017742118. doi: 10.1073/pnas.2017742118. Proc Natl Acad Sci U S A. 2021. PMID: 33446504 Free PMC article.
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders.
Brioschi S, Wang WL, Peng V, Wang M, Shchukina I, Greenberg ZJ, Bando JK, Jaeger N, Czepielewski RS, Swain A, Mogilenko DA, Beatty WL, Bayguinov P, Fitzpatrick JAJ, Schuettpelz LG, Fronick CC, Smirnov I, Kipnis J, Shapiro VS, Wu GF, Gilfillan S, Cella M, Artyomov MN, Kleinstein SH, Colonna M. Brioschi S, et al. Science. 2021 Jul 23;373(6553):eabf9277. doi: 10.1126/science.abf9277. Epub 2021 Jun 3. Science. 2021. PMID: 34083450 Free PMC article.
A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages.
Brioschi S, Belk JA, Peng V, Molgora M, Rodrigues PF, Nguyen KM, Wang S, Du S, Wang WL, Grajales-Reyes GE, Ponce JM, Yuede CM, Li Q, Baer JM, DeNardo DG, Gilfillan S, Cella M, Satpathy AT, Colonna M. Brioschi S, et al. Immunity. 2023 May 9;56(5):1027-1045.e8. doi: 10.1016/j.immuni.2023.01.028. Epub 2023 Feb 14. Immunity. 2023. PMID: 36791722 Free PMC article.
45 results