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Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial.
Hagel S, Bach F, Brenner T, Bracht H, Brinkmann A, Annecke T, Hohn A, Weigand M, Michels G, Kluge S, Nierhaus A, Jarczak D, König C, Weismann D, Frey O, Witzke D, Müller C, Bauer M, Kiehntopf M, Neugebauer S, Lehmann T, Roberts JA, Pletz MW; TARGET Trial Investigators. Hagel S, et al. Among authors: brinkmann a. Intensive Care Med. 2022 Mar;48(3):311-321. doi: 10.1007/s00134-021-06609-6. Epub 2022 Feb 1. Intensive Care Med. 2022. PMID: 35106617 Free PMC article. Clinical Trial.
Therapeutic drug monitoring-based dose optimisation of piperacillin/tazobactam to improve outcome in patients with sepsis (TARGET): a prospective, multi-centre, randomised controlled trial.
Hagel S, Fiedler S, Hohn A, Brinkmann A, Frey OR, Hoyer H, Schlattmann P, Kiehntopf M, Roberts JA, Pletz MW; TARGET Study Group. Hagel S, et al. Among authors: brinkmann a. Trials. 2019 Jun 6;20(1):330. doi: 10.1186/s13063-019-3437-x. Trials. 2019. PMID: 31171029 Free PMC article.
Therapeutic drug monitoring-guided continuous infusion of piperacillin/tazobactam significantly improves pharmacokinetic target attainment in critically ill patients: a retrospective analysis of four years of clinical experience.
Richter DC, Frey O, Röhr A, Roberts JA, Köberer A, Fuchs T, Papadimas N, Heinzel-Gutenbrunner M, Brenner T, Lichtenstern C, Weigand MA, Brinkmann A. Richter DC, et al. Among authors: brinkmann a. Infection. 2019 Dec;47(6):1001-1011. doi: 10.1007/s15010-019-01352-z. Epub 2019 Aug 31. Infection. 2019. PMID: 31473974
Correction to: Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial.
Hagel S, Bach F, Brenner T, Bracht H, Brinkmann A, Annecke T, Hohn A, Weigand MA, Michels G, Kluge S, Nierhaus A, Jarczak D, König C, Weismann D, Frey O, Witzke D, Müller C, Bauer M, Kiehntopf M, Neugebauer S, Lehmann T, Roberts JA, Pletz MW; TARGET Trial Investigators. Hagel S, et al. Among authors: brinkmann a. Intensive Care Med. 2022 May;48(5):646-647. doi: 10.1007/s00134-022-06668-3. Intensive Care Med. 2022. PMID: 35303118 Free PMC article. No abstract available.
Personalized ß-lactam dosing in patients with coronavirus disease 2019 (COVID-19) and pneumonia: A retrospective analysis on pharmacokinetics and pharmacokinetic target attainment.
Chiriac U, Frey OR, Roehr AC, Koeberer A, Gronau P, Fuchs T, Roberts JA, Brinkmann A. Chiriac U, et al. Among authors: brinkmann a. Medicine (Baltimore). 2021 Jun 4;100(22):e26253. doi: 10.1097/MD.0000000000026253. Medicine (Baltimore). 2021. PMID: 34087915 Free PMC article.
Personalized Piperacillin Dosing for the Critically Ill: A Retrospective Analysis of Clinical Experience with Dosing Software and Therapeutic Drug Monitoring to Optimize Antimicrobial Dosing.
Chiriac U, Richter DC, Frey OR, Röhr AC, Helbig S, Preisenberger J, Hagel S, Roberts JA, Weigand MA, Brinkmann A. Chiriac U, et al. Among authors: brinkmann a. Antibiotics (Basel). 2021 Jun 3;10(6):667. doi: 10.3390/antibiotics10060667. Antibiotics (Basel). 2021. PMID: 34205135 Free PMC article.
418 results