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iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome.
Landucci E, Brindisi M, Bianciardi L, Catania LM, Daga S, Croci S, Frullanti E, Fallerini C, Butini S, Brogi S, Furini S, Melani R, Molinaro A, Lorenzetti FC, Imperatore V, Amabile S, Mariani J, Mari F, Ariani F, Pizzorusso T, Pinto AM, Vaccarino FM, Renieri A, Campiani G, Meloni I. Landucci E, et al. Among authors: brindisi m. Exp Cell Res. 2018 Jul 15;368(2):225-235. doi: 10.1016/j.yexcr.2018.05.001. Epub 2018 May 4. Exp Cell Res. 2018. PMID: 29730163 Free PMC article.
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation.
Relitti N, Saraswati AP, Chemi G, Brindisi M, Brogi S, Herp D, Schmidtkunz K, Saccoccia F, Ruberti G, Ulivieri C, Vanni F, Sarno F, Altucci L, Lamponi S, Jung M, Gemma S, Butini S, Campiani G. Relitti N, et al. Among authors: brindisi m. Eur J Med Chem. 2021 Feb 15;212:112998. doi: 10.1016/j.ejmech.2020.112998. Epub 2020 Nov 7. Eur J Med Chem. 2021. PMID: 33199154
HCV-targeted antivirals: current status and future challenges.
Gemma S, Brogi S, Novellino E, Campiani G, Maga G, Brindisi M, Butini S. Gemma S, et al. Among authors: brindisi m. Curr Pharm Des. 2014;20(21):3445-64. doi: 10.2174/13816128113199990630. Curr Pharm Des. 2014. PMID: 24001232 Review.
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies.
Brindisi M, Senger J, Cavella C, Grillo A, Chemi G, Gemma S, Cucinella DM, Lamponi S, Sarno F, Iside C, Nebbioso A, Novellino E, Shaik TB, Romier C, Herp D, Jung M, Butini S, Campiani G, Altucci L, Brogi S. Brindisi M, et al. Eur J Med Chem. 2018 Sep 5;157:127-138. doi: 10.1016/j.ejmech.2018.07.069. Epub 2018 Jul 31. Eur J Med Chem. 2018. PMID: 30092367
175 results