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Synthesis of N-Hydroxy Isopeptide Containing Proteins.
Maity SK, Ohayon S, Brik A. Maity SK, et al. Among authors: brik a. Org Lett. 2015 Jul 17;17(14):3438-41. doi: 10.1021/acs.orglett.5b01443. Epub 2015 Jun 25. Org Lett. 2015. PMID: 26111051
Native chemical ligation at glutamine.
Siman P, Karthikeyan SV, Brik A. Siman P, et al. Among authors: brik a. Org Lett. 2012 Mar 16;14(6):1520-3. doi: 10.1021/ol300254y. Epub 2012 Feb 24. Org Lett. 2012. PMID: 22360701
N-methylation of isopeptide bond as a strategy to resist deubiquitinases.
Haj-Yahya M, Eltarteer N, Ohayon S, Shema E, Kotler E, Oren M, Brik A. Haj-Yahya M, et al. Among authors: brik a. Angew Chem Int Ed Engl. 2012 Nov 12;51(46):11535-9. doi: 10.1002/anie.201205771. Epub 2012 Oct 12. Angew Chem Int Ed Engl. 2012. PMID: 23065695 No abstract available.
Modifying the vicinity of the isopeptide bond to reveal differential behavior of ubiquitin chains with interacting proteins: organic chemistry applied to synthetic proteins.
Haj-Yahya N, Haj-Yahya M, Castañeda CA, Spasser L, Hemantha HP, Jbara M, Penner M, Ciechanover A, Fushman D, Brik A. Haj-Yahya N, et al. Among authors: brik a. Angew Chem Int Ed Engl. 2013 Oct 11;52(42):11149-53. doi: 10.1002/anie.201306118. Epub 2013 Sep 4. Angew Chem Int Ed Engl. 2013. PMID: 24006204 Free PMC article.
Dehydroalanine-based diubiquitin activity probes.
Haj-Yahya N, Hemantha HP, Meledin R, Bondalapati S, Seenaiah M, Brik A. Haj-Yahya N, et al. Among authors: brik a. Org Lett. 2014 Jan 17;16(2):540-3. doi: 10.1021/ol403416w. Epub 2013 Dec 24. Org Lett. 2014. PMID: 24364494
187 results