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The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity.
Nat Commun. 2018 May 29;9(1):2092. doi: 10.1038/s41467-018-04361-y.
Nat Commun. 2018.
PMID: 29844386
Free PMC article.
Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice.
Bricambert J, Miranda J, Benhamed F, Girard J, Postic C, Dentin R.
Bricambert J, et al.
J Clin Invest. 2010 Dec;120(12):4316-31. doi: 10.1172/JCI41624. Epub 2010 Nov 15.
J Clin Invest. 2010.
PMID: 21084751
Free PMC article.
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Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes.
Abderrahmani A, Yengo L, Caiazzo R, Canouil M, Cauchi S, Raverdy V, Plaisance V, Pawlowski V, Lobbens S, Maillet J, Rolland L, Boutry R, Queniat G, Kwapich M, Tenenbaum M, Bricambert J, Saussenthaler S, Anthony E, Jha P, Derop J, Sand O, Rabearivelo I, Leloire A, Pigeyre M, Daujat-Chavanieu M, Gerbal-Chaloin S, Dayeh T, Lassailly G, Mathurin P, Staels B, Auwerx J, Schürmann A, Postic C, Schafmayer C, Hampe J, Bonnefond A, Pattou F, Froguel P.
Abderrahmani A, et al. Among authors: bricambert j.
Diabetes. 2018 Jul;67(7):1310-1321. doi: 10.2337/db17-1539. Epub 2018 May 4.
Diabetes. 2018.
PMID: 29728363
Free article.
Clinical Trial.
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Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function.
Bricambert J, Favre D, Brajkovic S, Bonnefond A, Boutry R, Salvi R, Plaisance V, Chikri M, Chinetti-Gbaguidi G, Staels B, Giusti V, Caiazzo R, Pattou F, Waeber G, Froguel P, Abderrahmani A.
Bricambert J, et al.
Mol Metab. 2016 Oct 5;5(12):1200-1207. doi: 10.1016/j.molmet.2016.09.011. eCollection 2016 Dec.
Mol Metab. 2016.
PMID: 27900262
Free PMC article.
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