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Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO).
Shi Y, Cui M, Ochs K, Brendel M, Strübing FL, Briel N, Eckenweber F, Zou C, Banati RB, Liu GJ, Middleton RJ, Rupprecht R, Rudolph U, Zeilhofer HU, Rammes G, Herms J, Dorostkar MM. Shi Y, et al. Among authors: brendel m. Nat Neurosci. 2022 Mar;25(3):317-329. doi: 10.1038/s41593-022-01013-9. Epub 2022 Feb 28. Nat Neurosci. 2022. PMID: 35228700
Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [(18)F]-Florbetaben PET Quantitation in Alzheimer's Model Mice.
Overhoff F, Brendel M, Jaworska A, Korzhova V, Delker A, Probst F, Focke C, Gildehaus FJ, Carlsen J, Baumann K, Haass C, Bartenstein P, Herms J, Rominger A. Overhoff F, et al. Among authors: brendel m. Front Neurosci. 2016 Feb 29;10:45. doi: 10.3389/fnins.2016.00045. eCollection 2016. Front Neurosci. 2016. PMID: 26973442 Free PMC article.
Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.
Brendel M, Kleinberger G, Probst F, Jaworska A, Overhoff F, Blume T, Albert NL, Carlsen J, Lindner S, Gildehaus FJ, Ozmen L, Suárez-Calvet M, Bartenstein P, Baumann K, Ewers M, Herms J, Haass C, Rominger A. Brendel M, et al. Front Aging Neurosci. 2017 Jan 31;9:8. doi: 10.3389/fnagi.2017.00008. eCollection 2017. Front Aging Neurosci. 2017. PMID: 28197095 Free PMC article.
Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study.
Brendel M, Focke C, Blume T, Peters F, Deussing M, Probst F, Jaworska A, Overhoff F, Albert N, Lindner S, von Ungern-Sternberg B, Bartenstein P, Haass C, Kleinberger G, Herms J, Rominger A. Brendel M, et al. J Nucl Med. 2017 Dec;58(12):1984-1990. doi: 10.2967/jnumed.117.195107. Epub 2017 Jul 13. J Nucl Med. 2017. PMID: 28705919 Free article.
TSPO PET for glioma imaging using the novel ligand 18F-GE-180: first results in patients with glioblastoma.
Albert NL, Unterrainer M, Fleischmann DF, Lindner S, Vettermann F, Brunegraf A, Vomacka L, Brendel M, Wenter V, Wetzel C, Rupprecht R, Tonn JC, Belka C, Bartenstein P, Niyazi M. Albert NL, et al. Among authors: brendel m. Eur J Nucl Med Mol Imaging. 2017 Dec;44(13):2230-2238. doi: 10.1007/s00259-017-3799-9. Epub 2017 Aug 19. Eur J Nucl Med Mol Imaging. 2017. PMID: 28821920
Coupling between physiological TSPO expression in brain and myocardium allows stabilization of late-phase cerebral [18F]GE180 PET quantification.
Deussing M, Blume T, Vomacka L, Mahler C, Focke C, Todica A, Unterrainer M, Albert NL, Lindner S, von Ungern-Sternberg B, Baumann K, Zwergal A, Bartenstein P, Herms J, Rominger A, Brendel M. Deussing M, et al. Among authors: brendel m. Neuroimage. 2018 Jan 15;165:83-91. doi: 10.1016/j.neuroimage.2017.10.006. Epub 2017 Oct 5. Neuroimage. 2018. PMID: 28988133
TSPO imaging using the novel PET ligand [18F]GE-180: quantification approaches in patients with multiple sclerosis.
Vomacka L, Albert NL, Lindner S, Unterrainer M, Mahler C, Brendel M, Ermoschkin L, Gosewisch A, Brunegraf A, Buckley C, Kümpfel T, Rupprecht R, Ziegler S, Kerschensteiner M, Bartenstein P, Böning G. Vomacka L, et al. Among authors: brendel m. EJNMMI Res. 2017 Oct 26;7(1):89. doi: 10.1186/s13550-017-0340-x. EJNMMI Res. 2017. PMID: 29150726 Free PMC article.
546 results