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The drug-induced phenotypic landscape of colorectal cancer organoids.
Betge J, Rindtorff N, Sauer J, Rauscher B, Dingert C, Gaitantzi H, Herweck F, Srour-Mhanna K, Miersch T, Valentini E, Boonekamp KE, Hauber V, Gutting T, Frank L, Belle S, Gaiser T, Buchholz I, Jesenofsky R, Härtel N, Zhan T, Fischer B, Breitkopf-Heinlein K, Burgermeister E, Ebert MP, Boutros M. Betge J, et al. Among authors: breitkopf heinlein k. Nat Commun. 2022 Jun 6;13(1):3135. doi: 10.1038/s41467-022-30722-9. Nat Commun. 2022. PMID: 35668108 Free PMC article.
In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells.
Ramachandran SD, Schirmer K, Münst B, Heinz S, Ghafoory S, Wölfl S, Simon-Keller K, Marx A, Øie CI, Ebert MP, Walles H, Braspenning J, Breitkopf-Heinlein K. Ramachandran SD, et al. PLoS One. 2015 Oct 21;10(10):e0139345. doi: 10.1371/journal.pone.0139345. eCollection 2015. PLoS One. 2015. PMID: 26488607 Free PMC article.
Angiocrine Bmp2 signaling in murine liver controls normal iron homeostasis.
Koch PS, Olsavszky V, Ulbrich F, Sticht C, Demory A, Leibing T, Henzler T, Meyer M, Zierow J, Schneider S, Breitkopf-Heinlein K, Gaitantzi H, Spencer-Dene B, Arnold B, Klapproth K, Schledzewski K, Goerdt S, Géraud C. Koch PS, et al. Blood. 2017 Jan 26;129(4):415-419. doi: 10.1182/blood-2016-07-729822. Epub 2016 Nov 30. Blood. 2017. PMID: 27903529 Free PMC article.
BMP-9 interferes with liver regeneration and promotes liver fibrosis.
Breitkopf-Heinlein K, Meyer C, König C, Gaitantzi H, Addante A, Thomas M, Wiercinska E, Cai C, Li Q, Wan F, Hellerbrand C, Valous NA, Hahnel M, Ehlting C, Bode JG, Müller-Bohl S, Klingmüller U, Altenöder J, Ilkavets I, Goumans MJ, Hawinkels LJ, Lee SJ, Wieland M, Mogler C, Ebert MP, Herrera B, Augustin H, Sánchez A, Dooley S, Ten Dijke P. Breitkopf-Heinlein K, et al. Gut. 2017 May;66(5):939-954. doi: 10.1136/gutjnl-2016-313314. Epub 2017 Mar 23. Gut. 2017. PMID: 28336518
Epigenetic silencing of tumor suppressor candidate 3 confers adverse prognosis in early colorectal cancer.
Burgermeister E, Höde P, Betge J, Gutting T, Merkel A, Wu W, Tänzer M, Mossner M, Nowak D, Magdeburg J, Rückert F, Sticht C, Breitkopf-Heinlein K, Schulte N, Härtel N, Belle S, Post S, Gaiser T, Heppner BI, Behrens HM, Röcken C, Ebert MPA. Burgermeister E, et al. Oncotarget. 2017 Sep 15;8(49):84714-84728. doi: 10.18632/oncotarget.20950. eCollection 2017 Oct 17. Oncotarget. 2017. PMID: 29156678 Free PMC article.
Ethanol sensitizes hepatocytes for TGF-β-triggered apoptosis.
Gaitantzi H, Meyer C, Rakoczy P, Thomas M, Wahl K, Wandrer F, Bantel H, Alborzinia H, Wölfl S, Ehnert S, Nüssler A, Bergheim I, Ciuclan L, Ebert M, Breitkopf-Heinlein K, Dooley S. Gaitantzi H, et al. Among authors: breitkopf heinlein k. Cell Death Dis. 2018 Jan 19;9(2):51. doi: 10.1038/s41419-017-0071-y. Cell Death Dis. 2018. PMID: 29352207 Free PMC article.
Downregulation of SPARC Is Associated with Epithelial-Mesenchymal Transition and Low Differentiation State of Biliary Tract Cancer Cells.
Aghamaliyev U, Gaitantzi H, Thomas M, Simon-Keller K, Gaiser T, Marx A, Yagublu V, Araos J, Cai C, Valous NA, Halama N, Kiesslich T, Ebert M, Grützmann R, Rückert F, Breitkopf-Heinlein K. Aghamaliyev U, et al. Among authors: breitkopf heinlein k. Eur Surg Res. 2019;60(1-2):1-12. doi: 10.1159/000494734. Epub 2019 Jan 16. Eur Surg Res. 2019. PMID: 30650425
BMP-9 Modulates the Hepatic Responses to LPS.
Gaitantzi H, Karch J, Germann L, Cai C, Rausch V, Birgin E, Rahbari N, Seitz T, Hellerbrand C, König C, Augustin HG, Mogler C, de la Torre C, Gretz N, Itzel T, Teufel A, Ebert MPA, Breitkopf-Heinlein K. Gaitantzi H, et al. Among authors: breitkopf heinlein k. Cells. 2020 Mar 4;9(3):617. doi: 10.3390/cells9030617. Cells. 2020. PMID: 32143367 Free PMC article.
35 results