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Inhibitors of dihydroorotate dehydrogenase cooperate with molnupiravir and N4-hydroxycytidine to suppress SARS-CoV-2 replication.
Stegmann KM, Dickmanns A, Heinen N, Blaurock C, Karrasch T, Breithaupt A, Klopfleisch R, Uhlig N, Eberlein V, Issmail L, Herrmann ST, Schreieck A, Peelen E, Kohlhof H, Sadeghi B, Riek A, Speakman JR, Groß U, Görlich D, Vitt D, Müller T, Grunwald T, Pfaender S, Balkema-Buschmann A, Dobbelstein M. Stegmann KM, et al. Among authors: breithaupt a. iScience. 2022 May 20;25(5):104293. doi: 10.1016/j.isci.2022.104293. Epub 2022 Apr 25. iScience. 2022. PMID: 35492218 Free PMC article.
Aging and Senescence in Canine Testes.
Merz SE, Klopfleisch R, Breithaupt A, Gruber AD. Merz SE, et al. Among authors: breithaupt a. Vet Pathol. 2019 Sep;56(5):715-724. doi: 10.1177/0300985819843683. Epub 2019 May 6. Vet Pathol. 2019. PMID: 31060479
SARS-CoV-2 in fruit bats, ferrets, pigs, and chickens: an experimental transmission study.
Schlottau K, Rissmann M, Graaf A, Schön J, Sehl J, Wylezich C, Höper D, Mettenleiter TC, Balkema-Buschmann A, Harder T, Grund C, Hoffmann D, Breithaupt A, Beer M. Schlottau K, et al. Among authors: breithaupt a. Lancet Microbe. 2020 Sep;1(5):e218-e225. doi: 10.1016/S2666-5247(20)30089-6. Epub 2020 Jul 7. Lancet Microbe. 2020. PMID: 32838346 Free PMC article.
Genetic incompatibilities and reduced transmission in chickens may limit the evolution of reassortants between H9N2 and panzootic H5N8 clade 2.3.4.4 avian influenza virus showing high virulence for mammals.
Mostafa A, Blaurock C, Scheibner D, Müller C, Blohm U, Schäfer A, Gischke M, Salaheldin AH, Nooh HZ, Ali MA, Breithaupt A, Mettenleiter TC, Pleschka S, Abdelwhab EM. Mostafa A, et al. Among authors: breithaupt a. Virus Evol. 2020 Oct 15;6(2):veaa077. doi: 10.1093/ve/veaa077. eCollection 2020 Jul. Virus Evol. 2020. PMID: 33343923 Free PMC article.
The role of glycosylation in the N-terminus of the hemagglutinin of a unique H4N2 with a natural polybasic cleavage site in virus fitness in vitro and in vivo.
Gischke M, Bagato O, Breithaupt A, Scheibner D, Blaurock C, Vallbracht M, Karger A, Crossley B, Veits J, Böttcher-Friebertshäuser E, Mettenleiter TC, Abdelwhab EM. Gischke M, et al. Among authors: breithaupt a. Virulence. 2021 Dec;12(1):666-678. doi: 10.1080/21505594.2021.1881344. Virulence. 2021. PMID: 33538209 Free PMC article.
Egyptian Fruit Bats (Rousettus aegyptiacus) Were Resistant to Experimental Inoculation with Avian-Origin Influenza A Virus of Subtype H9N2, But Are Susceptible to Experimental Infection with Bat-Borne H9N2 Virus.
Halwe NJ, Gorka M, Hoffmann B, Rissmann M, Breithaupt A, Schwemmle M, Beer M, Kandeil A, Ali MA, Kayali G, Hoffmann D, Balkema-Buschmann A. Halwe NJ, et al. Among authors: breithaupt a. Viruses. 2021 Apr 14;13(4):672. doi: 10.3390/v13040672. Viruses. 2021. PMID: 33919890 Free PMC article.
Preferential Selection and Contribution of Non-Structural Protein 1 (NS1) to the Efficient Transmission of Panzootic Avian Influenza H5N8 Virus Clades 2.3.4.4A and B in Chickens and Ducks.
Blaurock C, Breithaupt A, Scheibner D, Bagato O, Karger A, Mettenleiter TC, Abdelwhab EM. Blaurock C, et al. Among authors: breithaupt a. J Virol. 2021 Aug 25;95(18):e0044521. doi: 10.1128/JVI.00445-21. Epub 2021 Aug 25. J Virol. 2021. PMID: 34160261 Free PMC article.
104 results