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HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.
Franke K, Kalucka J, Mamlouk S, Singh RP, Muschter A, Weidemann A, Iyengar V, Jahn S, Wieczorek K, Geiger K, Muders M, Sykes AM, Poitz DM, Ripich T, Otto T, Bergmann S, Breier G, Baretton G, Fong GH, Greaves DR, Bornstein S, Chavakis T, Fandrey J, Gassmann M, Wielockx B. Franke K, et al. Among authors: breier g. Blood. 2013 Feb 21;121(8):1436-45. doi: 10.1182/blood-2012-08-449181. Epub 2012 Dec 20. Blood. 2013. PMID: 23264599 Free PMC article.
HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress.
Singh RP, Franke K, Kalucka J, Mamlouk S, Muschter A, Gembarska A, Grinenko T, Willam C, Naumann R, Anastassiadis K, Stewart AF, Bornstein S, Chavakis T, Breier G, Waskow C, Wielockx B. Singh RP, et al. Among authors: breier g. Blood. 2013 Jun 27;121(26):5158-66. doi: 10.1182/blood-2012-12-471185. Epub 2013 May 10. Blood. 2013. PMID: 23667053 Free article.
HIF in vascular development and tumour angiogenesis.
Breier G, Licht AH, Nicolaus A, Klotzsche A, Wielockx B, Kirsnerova Z. Breier G, et al. Novartis Found Symp. 2007;283:126-33; discussion 133-8, 238-41. doi: 10.1002/9780470319413.ch10. Novartis Found Symp. 2007. PMID: 18300418
110 results