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The Genetic Links to Anxiety and Depression (GLAD) Study: Online recruitment into the largest recontactable study of depression and anxiety.
Davies MR, Kalsi G, Armour C, Jones IR, McIntosh AM, Smith DJ, Walters JTR, Bradley JR, Kingston N, Ashford S, Beange I, Brailean A, Cleare AJ, Coleman JRI, Curtis CJ, Curzons SCB, Davis KAS, Dowey LRC, Gault VA, Goldsmith KA, Bennett MH, Hirose Y, Hotopf M, Hübel C, Kanz C, Leng J, Lyall DM, Mason BD, McAtarsney-Kovacs M, Monssen D, Moulton A, Ovington N, Palaiologou E, Pariante CM, Parikh S, Peel AJ, Price RK, Rimes KA, Rogers HC, Sambrook J, Skelton M, Spaul A, Suarez ELA, Sykes BL, Thomas KG, Young AH, Vassos E, Veale D, White KM, Wingrove J; NIHR BioResource consortium; Eley TC, Breen G. Davies MR, et al. Among authors: breen g. Behav Res Ther. 2019 Dec;123:103503. doi: 10.1016/j.brat.2019.103503. Epub 2019 Oct 24. Behav Res Ther. 2019. PMID: 31715324 Free PMC article.
Dissecting the genetic heterogeneity of depression through age at onset.
Power RA, Keers R, Ng MY, Butler AW, Uher R, Cohen-Woods S, Ising M, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Hauser J, Henigsberg N, Maier W, Zobel A, Mors O, Placentino AS, Rietschel M, Souery D, Kozel D, Preisig M, Lucae S, Binder EB, Aitchison KJ, Tozzi F, Muglia P, Breen G, Craig IW, Farmer AE, Müller-Myhsok B, McGuffin P, Lewis CM. Power RA, et al. Among authors: breen g. Am J Med Genet B Neuropsychiatr Genet. 2012 Oct;159B(7):859-68. doi: 10.1002/ajmg.b.32093. Epub 2012 Aug 22. Am J Med Genet B Neuropsychiatr Genet. 2012. PMID: 22915352
Clinical Predictors of Response to Cognitive-Behavioral Therapy in Pediatric Anxiety Disorders: The Genes for Treatment (GxT) Study.
Hudson JL, Keers R, Roberts S, Coleman JR, Breen G, Arendt K, Bögels S, Cooper P, Creswell C, Hartman C, Heiervang ER, Hötzel K, In-Albon T, Lavallee K, Lyneham HJ, Marin CE, McKinnon A, Meiser-Stedman R, Morris T, Nauta M, Rapee RM, Schneider S, Schneider SC, Silverman WK, Thastum M, Thirlwall K, Waite P, Wergeland GJ, Lester KJ, Eley TC. Hudson JL, et al. Among authors: breen g. J Am Acad Child Adolesc Psychiatry. 2015 Jun;54(6):454-63. doi: 10.1016/j.jaac.2015.03.018. Epub 2015 Apr 1. J Am Acad Child Adolesc Psychiatry. 2015. PMID: 26004660 Free PMC article. Clinical Trial.
Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders.
Lester KJ, Roberts S, Keers R, Coleman JR, Breen G, Wong CC, Xu X, Arendt K, Blatter-Meunier J, Bögels S, Cooper P, Creswell C, Heiervang ER, Herren C, Hogendoorn SM, Hudson JL, Krause K, Lyneham HJ, McKinnon A, Morris T, Nauta MH, Rapee RM, Rey Y, Schneider S, Schneider SC, Silverman WK, Smith P, Thastum M, Thirlwall K, Waite P, Wergeland GJ, Eley TC. Lester KJ, et al. Among authors: breen g. Br J Psychiatry. 2016 Feb;208(2):182-8. doi: 10.1192/bjp.bp.114.154997. Epub 2015 Aug 20. Br J Psychiatry. 2016. PMID: 26294368 Free PMC article. Clinical Trial.
HPA AXIS RELATED GENES AND RESPONSE TO PSYCHOLOGICAL THERAPIES: GENETICS AND EPIGENETICS.
Roberts S, Keers R, Lester KJ, Coleman JR, Breen G, Arendt K, Blatter-Meunier J, Cooper P, Creswell C, Fjermestad K, Havik OE, Herren C, Hogendoorn SM, Hudson JL, Krause K, Lyneham HJ, Morris T, Nauta M, Rapee RM, Rey Y, Schneider S, Schneider SC, Silverman WK, Thastum M, Thirlwall K, Waite P, Eley TC, Wong CC. Roberts S, et al. Among authors: breen g. Depress Anxiety. 2015 Dec;32(12):861-70. doi: 10.1002/da.22430. Epub 2015 Oct 7. Depress Anxiety. 2015. PMID: 26647360 Free PMC article.
Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.
Singh T, Kurki MI, Curtis D, Purcell SM, Crooks L, McRae J, Suvisaari J, Chheda H, Blackwood D, Breen G, Pietiläinen O, Gerety SS, Ayub M, Blyth M, Cole T, Collier D, Coomber EL, Craddock N, Daly MJ, Danesh J, DiForti M, Foster A, Freimer NB, Geschwind D, Johnstone M, Joss S, Kirov G, Körkkö J, Kuismin O, Holmans P, Hultman CM, Iyegbe C, Lönnqvist J, Männikkö M, McCarroll SA, McGuffin P, McIntosh AM, McQuillin A, Moilanen JS, Moore C, Murray RM, Newbury-Ecob R, Ouwehand W, Paunio T, Prigmore E, Rees E, Roberts D, Sambrook J, Sklar P, St Clair D, Veijola J, Walters JT, Williams H; Swedish Schizophrenia Study; INTERVAL Study; DDD Study; UK10 K Consortium; Sullivan PF, Hurles ME, O'Donovan MC, Palotie A, Owen MJ, Barrett JC. Singh T, et al. Among authors: breen g. Nat Neurosci. 2016 Apr;19(4):571-7. doi: 10.1038/nn.4267. Epub 2016 Mar 14. Nat Neurosci. 2016. PMID: 26974950 Free PMC article.
Genome-wide association study of response to cognitive-behavioural therapy in children with anxiety disorders.
Coleman JR, Lester KJ, Keers R, Roberts S, Curtis C, Arendt K, Bögels S, Cooper P, Creswell C, Dalgleish T, Hartman CA, Heiervang ER, Hötzel K, Hudson JL, In-Albon T, Lavallee K, Lyneham HJ, Marin CE, Meiser-Stedman R, Morris T, Nauta MH, Rapee RM, Schneider S, Schneider SC, Silverman WK, Thastum M, Thirlwall K, Waite P, Wergeland GJ, Breen G, Eley TC. Coleman JR, et al. Among authors: breen g. Br J Psychiatry. 2016 Sep;209(3):236-43. doi: 10.1192/bjp.bp.115.168229. Epub 2016 Mar 17. Br J Psychiatry. 2016. PMID: 26989097 Free PMC article. Clinical Trial.
A Genome-Wide Test of the Differential Susceptibility Hypothesis Reveals a Genetic Predictor of Differential Response to Psychological Treatments for Child Anxiety Disorders.
Keers R, Coleman JR, Lester KJ, Roberts S, Breen G, Thastum M, Bögels S, Schneider S, Heiervang E, Meiser-Stedman R, Nauta M, Creswell C, Thirlwall K, Rapee RM, Hudson JL, Lewis C, Plomin R, Eley TC. Keers R, et al. Among authors: breen g. Psychother Psychosom. 2016;85(3):146-58. doi: 10.1159/000444023. Epub 2016 Apr 5. Psychother Psychosom. 2016. PMID: 27043157 Free PMC article.
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