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Coculture of primary human colon monolayer with human gut bacteria.
Zhang J, Hernandez-Gordillo V, Trapecar M, Wright C, Taketani M, Schneider K, Chen WLK, Stas E, Breault DT, Carrier RL, Voigt CA, Griffith LG. Zhang J, et al. Among authors: breault dt. Nat Protoc. 2021 Aug;16(8):3874-3900. doi: 10.1038/s41596-021-00562-w. Epub 2021 Jun 28. Nat Protoc. 2021. PMID: 34183870 Free PMC article.
β-Catenin-Driven Differentiation Is a Tissue-Specific Epigenetic Vulnerability in Adrenal Cancer.
Mohan DR, Borges KS, Finco I, LaPensee CR, Rege J, Solon AL, Little DW, Else T, Almeida MQ, Dang D, Haggerty-Skeans J, Apfelbaum AA, Vinco M, Wakamatsu A, Mariani BMP, Amorim LC, Latronico AC, Mendonca BB, Zerbini MCN, Lawlor ER, Ohi R, Auchus RJ, Rainey WE, Marie SKN, Giordano TJ, Venneti S, Fragoso MCBV, Breault DT, Lerario AM, Hammer GD. Mohan DR, et al. Among authors: breault dt. Cancer Res. 2023 Jul 5;83(13):2123-2141. doi: 10.1158/0008-5472.CAN-22-2712. Cancer Res. 2023. PMID: 37129912 Free PMC article.
A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip.
Jalili-Firoozinezhad S, Gazzaniga FS, Calamari EL, Camacho DM, Fadel CW, Bein A, Swenor B, Nestor B, Cronce MJ, Tovaglieri A, Levy O, Gregory KE, Breault DT, Cabral JMS, Kasper DL, Novak R, Ingber DE. Jalili-Firoozinezhad S, et al. Among authors: breault dt. Nat Biomed Eng. 2019 Jul;3(7):520-531. doi: 10.1038/s41551-019-0397-0. Epub 2019 May 13. Nat Biomed Eng. 2019. PMID: 31086325 Free PMC article.
Human Colon-on-a-Chip Enables Continuous In Vitro Analysis of Colon Mucus Layer Accumulation and Physiology.
Sontheimer-Phelps A, Chou DB, Tovaglieri A, Ferrante TC, Duckworth T, Fadel C, Frismantas V, Sutherland AD, Jalili-Firoozinezhad S, Kasendra M, Stas E, Weaver JC, Richmond CA, Levy O, Prantil-Baun R, Breault DT, Ingber DE. Sontheimer-Phelps A, et al. Among authors: breault dt. Cell Mol Gastroenterol Hepatol. 2020;9(3):507-526. doi: 10.1016/j.jcmgh.2019.11.008. Epub 2019 Nov 26. Cell Mol Gastroenterol Hepatol. 2020. PMID: 31778828 Free PMC article.
Primary human colonic mucosal barrier crosstalk with super oxygen-sensitive Faecalibacterium prausnitzii in continuous culture.
Zhang J, Huang YJ, Yoon JY, Kemmitt J, Wright C, Schneider K, Sphabmixay P, Hernandez-Gordillo V, Holcomb SJ, Bhushan B, Rohatgi G, Benton K, Carpenter D, Kester JC, Eng G, Breault DT, Yilmaz O, Taketani M, Voigt CA, Carrier RL, Trumper DL, Griffith LG. Zhang J, et al. Among authors: breault dt. Med. 2021 Jan 15;2(1):74-98.e9. doi: 10.1016/j.medj.2020.07.001. Epub 2020 Aug 6. Med. 2021. PMID: 33511375 Free PMC article.
Robust differentiation of human enteroendocrine cells from intestinal stem cells.
Zeve D, Stas E, de Sousa Casal J, Mannam P, Qi W, Yin X, Dubois S, Shah MS, Syverson EP, Hafner S, Karp JM, Carlone DL, Ordovas-Montanes J, Breault DT. Zeve D, et al. Among authors: breault dt. Nat Commun. 2022 Jan 11;13(1):261. doi: 10.1038/s41467-021-27901-5. Nat Commun. 2022. PMID: 35017529 Free PMC article.
Stiffness Restricts the Stemness of the Intestinal Stem Cells and Skews Their Differentiation Toward Goblet Cells.
He S, Lei P, Kang W, Cheung P, Xu T, Mana M, Park CY, Wang H, Imada S, Russell JO, Wang J, Wang R, Zhou Z, Chetal K, Stas E, Mohad V, Bruun-Rasmussen P, Sadreyev RI, Hodin RA, Zhang Y, Breault DT, Camargo FD, Yilmaz ÖH, Fredberg JJ, Saeidi N. He S, et al. Among authors: breault dt. Gastroenterology. 2023 Jun;164(7):1137-1151.e15. doi: 10.1053/j.gastro.2023.02.030. Epub 2023 Mar 4. Gastroenterology. 2023. PMID: 36871599
101 results