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Base-Edited CAR7 T Cells for Relapsed T-Cell Acute Lymphoblastic Leukemia.
N Engl J Med. 2023 Sep 7;389(10):899-910. doi: 10.1056/NEJMoa2300709. Epub 2023 Jun 14.
N Engl J Med. 2023.
PMID: 37314354
Clinical Trial.
Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia.
Ottaviano G, Georgiadis C, Gkazi SA, Syed F, Zhan H, Etuk A, Preece R, Chu J, Kubat A, Adams S, Veys P, Vora A, Rao K, Qasim W; TT52 CRISPR-CAR group.
Ottaviano G, et al.
Sci Transl Med. 2022 Oct 26;14(668):eabq3010. doi: 10.1126/scitranslmed.abq3010. Epub 2022 Oct 26.
Sci Transl Med. 2022.
PMID: 36288281
Clinical Trial.
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