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Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Hibshman GN, Bravo JPK, Hooper MM, Dangerfield TL, Zhang H, Finkelstein IJ, Johnson KA, Taylor DW. Hibshman GN, et al. Among authors: bravo jpk. Nat Commun. 2024 Apr 30;15(1):3663. doi: 10.1038/s41467-024-47830-3. Nat Commun. 2024. PMID: 38688943 Free PMC article.
RNA targeting and cleavage by the type III-Dv CRISPR effector complex.
Schwartz EA, Bravo JPK, Ahsan M, Macias LA, McCafferty CL, Dangerfield TL, Walker JN, Brodbelt JS, Palermo G, Fineran PC, Fagerlund RD, Taylor DW. Schwartz EA, et al. Among authors: bravo jpk. Nat Commun. 2024 Apr 18;15(1):3324. doi: 10.1038/s41467-024-47506-y. Nat Commun. 2024. PMID: 38637512 Free PMC article.
Lipid droplets as substrates for protein phase separation.
Kamatar A, Bravo JPK, Yuan F, Wang L, Lafer EM, Taylor DW, Stachowiak JC, Parekh SH. Kamatar A, et al. Among authors: bravo jpk. Biophys J. 2024 Mar 11:S0006-3495(24)00180-2. doi: 10.1016/j.bpj.2024.03.015. Online ahead of print. Biophys J. 2024. PMID: 38462838
Type III-B CRISPR-Cas cascade of proteolytic cleavages.
Steens JA, Bravo JPK, Salazar CRP, Yildiz C, Amieiro AM, Köstlbacher S, Prinsen SHP, Andres AS, Patinios C, Bardis A, Barendregt A, Scheltema RA, Ettema TJG, van der Oost J, Taylor DW, Staals RHJ. Steens JA, et al. Among authors: bravo jpk. Science. 2024 Feb 2;383(6682):512-519. doi: 10.1126/science.adk0378. Epub 2024 Feb 1. Science. 2024. PMID: 38301007
Type III CRISPR-Cas complexes act as protein-assisted ribozymes during target RNA cleavage.
Schwartz EA, Bravo JPK, Ahsan M, Macias LA, McCafferty CL, Dangerfield TL, Walker JN, Brodbelt JS, Palermo G, Fineran PC, Fagerlund RD, Taylor DW. Schwartz EA, et al. Among authors: bravo jpk. Res Sq [Preprint]. 2023 Apr 27:rs.3.rs-2837968. doi: 10.21203/rs.3.rs-2837968/v1. Res Sq. 2023. PMID: 37163044 Free PMC article. Updated. Preprint.
Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
O'Brien RE, Bravo JPK, Ramos D, Hibshman GN, Wright JT, Taylor DW. O'Brien RE, et al. Among authors: bravo jpk. Mol Cell. 2023 Mar 2;83(5):746-758.e5. doi: 10.1016/j.molcel.2023.01.024. Epub 2023 Feb 16. Mol Cell. 2023. PMID: 36805026 Free PMC article.
35 results