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Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death.
Silvestre-Roig C, Braster Q, Wichapong K, Lee EY, Teulon JM, Berrebeh N, Winter J, Adrover JM, Santos GS, Froese A, Lemnitzer P, Ortega-Gómez A, Chevre R, Marschner J, Schumski A, Winter C, Perez-Olivares L, Pan C, Paulin N, Schoufour T, Hartwig H, González-Ramos S, Kamp F, Megens RTA, Mowen KA, Gunzer M, Maegdefessel L, Hackeng T, Lutgens E, Daemen M, von Blume J, Anders HJ, Nikolaev VO, Pellequer JL, Weber C, Hidalgo A, Nicolaes GAF, Wong GCL, Soehnlein O. Silvestre-Roig C, et al. Among authors: braster q. Nature. 2019 May;569(7755):236-240. doi: 10.1038/s41586-019-1167-6. Epub 2019 May 1. Nature. 2019. PMID: 31043745 Free PMC article.
Neutrophils as regulators of cardiovascular inflammation.
Silvestre-Roig C, Braster Q, Ortega-Gomez A, Soehnlein O. Silvestre-Roig C, et al. Among authors: braster q. Nat Rev Cardiol. 2020 Jun;17(6):327-340. doi: 10.1038/s41569-019-0326-7. Epub 2020 Jan 29. Nat Rev Cardiol. 2020. PMID: 31996800 Review.
Atherosclerotic Plaque Destabilization in Mice: A Comparative Study.
Hartwig H, Silvestre-Roig C, Hendrikse J, Beckers L, Paulin N, Van der Heiden K, Braster Q, Drechsler M, Daemen MJ, Lutgens E, Soehnlein O. Hartwig H, et al. Among authors: braster q. PLoS One. 2015 Oct 22;10(10):e0141019. doi: 10.1371/journal.pone.0141019. eCollection 2015. PLoS One. 2015. PMID: 26492161 Free PMC article.
Histone Deacetylase 9 Activates IKK to Regulate Atherosclerotic Plaque Vulnerability.
Asare Y, Campbell-James TA, Bokov Y, Yu LL, Prestel M, El Bounkari O, Roth S, Megens RTA, Straub T, Thomas K, Yan G, Schneider M, Ziesch N, Tiedt S, Silvestre-Roig C, Braster Q, Huang Y, Schneider M, Malik R, Haffner C, Liesz A, Soehnlein O, Bernhagen J, Dichgans M. Asare Y, et al. Among authors: braster q. Circ Res. 2020 Aug 28;127(6):811-823. doi: 10.1161/CIRCRESAHA.120.316743. Epub 2020 Jun 17. Circ Res. 2020. PMID: 32546048
Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis.
Hinterdobler J, Schott S, Jin H, Meesmann A, Steinsiek AL, Zimmermann AS, Wobst J, Müller P, Mauersberger C, Vilne B, Baecklund A, Chen CS, Moggio A, Braster Q, Molitor M, Krane M, Kempf WE, Ladwig KH, Hristov M, Hulsmans M, Hilgendorf I, Weber C, Wenzel P, Scheiermann C, Maegdefessel L, Soehnlein O, Libby P, Nahrendorf M, Schunkert H, Kessler T, Sager HB. Hinterdobler J, et al. Among authors: braster q. Eur Heart J. 2021 Oct 14;42(39):4077-4088. doi: 10.1093/eurheartj/ehab371. Eur Heart J. 2021. PMID: 34279021 Free PMC article.
Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases.
Chirivi RGS, van Rosmalen JWG, van der Linden M, Euler M, Schmets G, Bogatkevich G, Kambas K, Hahn J, Braster Q, Soehnlein O, Hoffmann MH, Es HHGV, Raats JMH. Chirivi RGS, et al. Among authors: braster q. Cell Mol Immunol. 2021 Jun;18(6):1528-1544. doi: 10.1038/s41423-020-0381-3. Epub 2020 Mar 20. Cell Mol Immunol. 2021. PMID: 32203195 Free PMC article.
Interleukin-1β suppression dampens inflammatory leucocyte production and uptake in atherosclerosis.
Hettwer J, Hinterdobler J, Miritsch B, Deutsch MA, Li X, Mauersberger C, Moggio A, Braster Q, Gram H, Robertson AAB, Cooper MA, Groß O, Krane M, Weber C, Koenig W, Soehnlein O, Adamstein NH, Ridker P, Schunkert H, Libby P, Kessler T, Sager HB. Hettwer J, et al. Among authors: braster q. Cardiovasc Res. 2022 Oct 21;118(13):2778-2791. doi: 10.1093/cvr/cvab337. Cardiovasc Res. 2022. PMID: 34718444 Free PMC article.