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7-Chloroquinolinotriazoles: synthesis by the azide-alkyne cycloaddition click chemistry, antimalarial activity, cytotoxicity and SAR studies.
Pereira GR, Brandão GC, Arantes LM, de Oliveira HA Jr, de Paula RC, do Nascimento MF, dos Santos FM, da Rocha RK, Lopes JC, de Oliveira AB. Pereira GR, et al. Among authors: brandao gc. Eur J Med Chem. 2014 Feb 12;73:295-309. doi: 10.1016/j.ejmech.2013.11.022. Epub 2013 Dec 1. Eur J Med Chem. 2014. PMID: 24469080
In vitro and in vivo antileishmanial activity of a fluoroquinoline derivate against Leishmania infantum and Leishmania amazonensis species.
Tavares GSV, Mendonça DVC, Lage DP, Antinarelli LMR, Soyer TG, Senna AJS, Matos GF, Dias DS, Ribeiro PAF, Batista JPT, Poletto JM, Brandão GC, Chávez-Fumagalli MA, Pereira GR, Coimbra ES, Coelho EAF. Tavares GSV, et al. Among authors: brandao gc. Acta Trop. 2019 Mar;191:29-37. doi: 10.1016/j.actatropica.2018.12.036. Epub 2018 Dec 23. Acta Trop. 2019. PMID: 30586571
A chloroquinoline derivate presents effective in vitro and in vivo antileishmanial activity against Leishmania species that cause tegumentary and visceral leishmaniasis.
Sousa JKT, Antinarelli LMR, Mendonça DVC, Lage DP, Tavares GSV, Dias DS, Ribeiro PAF, Ludolf F, Coelho VTS, Oliveira-da-Silva JA, Perin L, Oliveira BA, Alvarenga DF, Chávez-Fumagalli MA, Brandão GC, Nobre V, Pereira GR, Coimbra ES, Coelho EAF. Sousa JKT, et al. Among authors: brandao gc. Parasitol Int. 2019 Dec;73:101966. doi: 10.1016/j.parint.2019.101966. Epub 2019 Jul 27. Parasitol Int. 2019. PMID: 31362122
74 results