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XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells.
Wahida A, Müller M, Hiergeist A, Popper B, Steiger K, Branca C, Tschurtschenthaler M, Engleitner T, Donakonda S, De Coninck J, Öllinger R, Pfautsch MK, Müller N, Silva M, Usluer S, Thiele Orberg E, Böttcher JP, Pfarr N, Anton M, Slotta-Huspenina JB, Nerlich AG, Madl T, Basic M, Bleich A, Berx G, Ruland J, Knolle PA, Rad R, Adolph TE, Vandenabeele P, Kanegane H, Gessner A, Jost PJ, Yabal M. Wahida A, et al. Among authors: branca c. Sci Immunol. 2021 Nov 5;6(65):eabf7235. doi: 10.1126/sciimmunol.abf7235. Epub 2021 Nov 5. Sci Immunol. 2021. PMID: 34739338
MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically.
Munkhbaatar E, Dietzen M, Agrawal D, Anton M, Jesinghaus M, Boxberg M, Pfarr N, Bidola P, Uhrig S, Höckendorf U, Meinhardt AL, Wahida A, Heid I, Braren R, Mishra R, Warth A, Muley T, Poh PSP, Wang X, Fröhling S, Steiger K, Slotta-Huspenina J, van Griensven M, Pfeiffer F, Lange S, Rad R, Spella M, Stathopoulos GT, Ruland J, Bassermann F, Weichert W, Strasser A, Branca C, Heikenwalder M, Swanton C, McGranahan N, Jost PJ. Munkhbaatar E, et al. Among authors: branca c. Nat Commun. 2020 Sep 10;11(1):4527. doi: 10.1038/s41467-020-18372-1. Nat Commun. 2020. PMID: 32913197 Free PMC article.
Comprehensive characterization of central BCL-2 family members in aberrant eosinophils and their impact on therapeutic strategies.
Odinius TO, Buschhorn L, Wagner C, Hauch RT, Dill V, Dechant M, Buck MC, Shoumariyeh K, Moog P, Schwaab J, Reiter A, Brockow K, Götze K, Bassermann F, Höckendorf U, Branca C, Jost PJ, Jilg S. Odinius TO, et al. Among authors: branca c. J Cancer Res Clin Oncol. 2022 Feb;148(2):331-340. doi: 10.1007/s00432-021-03827-9. Epub 2021 Oct 15. J Cancer Res Clin Oncol. 2022. PMID: 34654952 Free PMC article.
Necroptosis activation in Alzheimer's disease.
Caccamo A, Branca C, Piras IS, Ferreira E, Huentelman MJ, Liang WS, Readhead B, Dudley JT, Spangenberg EE, Green KN, Belfiore R, Winslow W, Oddo S. Caccamo A, et al. Among authors: branca c. Nat Neurosci. 2017 Sep;20(9):1236-1246. doi: 10.1038/nn.4608. Epub 2017 Jul 24. Nat Neurosci. 2017. PMID: 28758999
Dyrk1 inhibition improves Alzheimer's disease-like pathology.
Branca C, Shaw DM, Belfiore R, Gokhale V, Shaw AY, Foley C, Smith B, Hulme C, Dunckley T, Meechoovet B, Caccamo A, Oddo S. Branca C, et al. Aging Cell. 2017 Oct;16(5):1146-1154. doi: 10.1111/acel.12648. Epub 2017 Aug 4. Aging Cell. 2017. PMID: 28779511 Free PMC article.
78 results