Bradshaw TD - Search Results

1

Jerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1).

Chung FF, Tan PF, Raja VJ, Tan BS, Lim KH, Kam TS, Hii LW, Tan SH, See SJ, Tan YF, Wong LZ, Yam WK, Mai CW, Bradshaw TD, Leong CO. Chung FF, et al. Among authors: bradshaw td. Sci Rep. 2017 Feb 15;7:42504. doi: 10.1038/srep42504. Sci Rep. 2017. PMID: 28198434 Free PMC article.

2

Mechanisms of acquired resistance to 2-(4-Amino-3-methylphenyl)benzothiazole in breast cancer cell lines.

Bradshaw TD, Stone EL, Trapani V, Leong CO, Matthews CS, te Poele R, Stevens MF. Bradshaw TD, et al. Breast Cancer Res Treat. 2008 Jul;110(1):57-68. doi: 10.1007/s10549-007-9690-9. Epub 2007 Aug 3. Breast Cancer Res Treat. 2008. PMID: 17674193

3

CYP2S1 and CYP2W1 mediate 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW-610, NSC 721648) sensitivity in breast and colorectal cancer cells.

Tan BS, Tiong KH, Muruhadas A, Randhawa N, Choo HL, Bradshaw TD, Stevens MF, Leong CO. Tan BS, et al. Among authors: bradshaw td. Mol Cancer Ther. 2011 Oct;10(10):1982-92. doi: 10.1158/1535-7163.MCT-11-0391. Epub 2011 Aug 10. Mol Cancer Ther. 2011. PMID: 21831963

4

Acalypha wilkesiana extracts induce apoptosis by causing single strand and double strand DNA breaks.

Lim SW, Ting KN, Bradshaw TD, Zeenathul NA, Wiart C, Khoo TJ, Lim KH, Loh HS. Lim SW, et al. Among authors: bradshaw td. J Ethnopharmacol. 2011 Nov 18;138(2):616-23. doi: 10.1016/j.jep.2011.10.005. Epub 2011 Oct 12. J Ethnopharmacol. 2011. PMID: 22008878

5

6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor γ (PPARγ).

Tan BS, Kang O, Mai CW, Tiong KH, Khoo AS, Pichika MR, Bradshaw TD, Leong CO. Tan BS, et al. Among authors: bradshaw td. Cancer Lett. 2013 Aug 9;336(1):127-39. doi: 10.1016/j.canlet.2013.04.014. Epub 2013 Apr 21. Cancer Lett. 2013. PMID: 23612072

6

Novel antitumour indole alkaloid, Jerantinine A, evokes potent G2/M cell cycle arrest targeting microtubules.

Raja VJ, Lim KH, Leong CO, Kam TS, Bradshaw TD. Raja VJ, et al. Among authors: bradshaw td. Invest New Drugs. 2014 Oct;32(5):838-50. doi: 10.1007/s10637-014-0126-1. Epub 2014 Jun 15. Invest New Drugs. 2014. PMID: 24927857

7

Ibogan, tacaman, and cytotoxic bisindole alkaloids from tabernaemontana. Cononusine, an iboga alkaloid with unusual incorporation of a pyrrolidone moiety.

Lim KH, Raja VJ, Bradshaw TD, Lim SH, Low YY, Kam TS. Lim KH, et al. Among authors: bradshaw td. J Nat Prod. 2015 May 22;78(5):1129-38. doi: 10.1021/acs.jnatprod.5b00117. Epub 2015 Apr 28. J Nat Prod. 2015. PMID: 25919190

8

Antitumour benzothiazoles. Part 32: DNA adducts and double strand breaks correlate with activity; synthesis of 5F203 hydrogels for local delivery.

Stone EL, Citossi F, Singh R, Kaur B, Gaskell M, Farmer PB, Monks A, Hose C, Stevens MF, Leong CO, Stocks M, Kellam B, Marlow M, Bradshaw TD. Stone EL, et al. Among authors: bradshaw td. Bioorg Med Chem. 2015 Nov 1;23(21):6891-9. doi: 10.1016/j.bmc.2015.09.052. Epub 2015 Oct 3. Bioorg Med Chem. 2015. PMID: 26474663

9

In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B.

Qazzaz ME, Raja VJ, Lim KH, Kam TS, Lee JB, Gershkovich P, Bradshaw TD. Qazzaz ME, et al. Among authors: bradshaw td. Cancer Lett. 2016 Jan 28;370(2):185-97. doi: 10.1016/j.canlet.2015.10.013. Epub 2015 Oct 26. Cancer Lett. 2016. PMID: 26515390 Free article.

10

Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway.

Soo HC, Chung FF, Lim KH, Yap VA, Bradshaw TD, Hii LW, Tan SH, See SJ, Tan YF, Leong CO, Mai CW. Soo HC, et al. Among authors: bradshaw td. PLoS One. 2017 Jan 20;12(1):e0170551. doi: 10.1371/journal.pone.0170551. eCollection 2017. PLoS One. 2017. PMID: 28107519 Free PMC article.

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