Braddock D - Search Results

1

Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition.

Crichlow GV, Zhou H, Hsiao HH, Frederick KB, Debrosse M, Yang Y, Folta-Stogniew EJ, Chung HJ, Fan C, De la Cruz EM, Levens D, Lolis E, Braddock D. Crichlow GV, et al. Among authors: braddock d. EMBO J. 2008 Jan 9;27(1):277-89. doi: 10.1038/sj.emboj.7601936. Epub 2007 Dec 6. EMBO J. 2008. PMID: 18059478 Free PMC article.

2

Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.

Hsiao HT, Crichlow GV, Murphy JW, Folta-Stogniew EJ, Lolis EJ, Braddock DT. Hsiao HT, et al. PLoS One. 2020 Nov 30;15(11):e0242725. doi: 10.1371/journal.pone.0242725. eCollection 2020. PLoS One. 2020. PMID: 33253191 Free PMC article.

3

Quantitative characterization of the interactions among c-myc transcriptional regulators FUSE, FBP, and FIR.

Hsiao HH, Nath A, Lin CY, Folta-Stogniew EJ, Rhoades E, Braddock DT. Hsiao HH, et al. Biochemistry. 2010 Jun 8;49(22):4620-34. doi: 10.1021/bi9021445. Biochemistry. 2010. PMID: 20420426

4

Molecular basis of sequence-specific single-stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single-stranded DNA.

Braddock DT, Baber JL, Levens D, Clore GM. Braddock DT, et al. EMBO J. 2002 Jul 1;21(13):3476-85. doi: 10.1093/emboj/cdf352. EMBO J. 2002. PMID: 12093748 Free PMC article.

5

Kinetic analysis of autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution.

Saunders LP, Cao W, Chang WC, Albright RA, Braddock DT, De La Cruz EM. Saunders LP, et al. J Biol Chem. 2011 Aug 26;286(34):30130-41. doi: 10.1074/jbc.M111.246884. Epub 2011 Jun 30. J Biol Chem. 2011. PMID: 21719699 Free PMC article.

6

Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion.

Saunders LP, Ouellette A, Bandle R, Chang WC, Zhou H, Misra RN, De La Cruz EM, Braddock DT. Saunders LP, et al. Mol Cancer Ther. 2008 Oct;7(10):3352-62. doi: 10.1158/1535-7163.MCT-08-0463. Mol Cancer Ther. 2008. PMID: 18852138 Free PMC article.

7

Structure and dynamics of KH domains from FBP bound to single-stranded DNA.

Braddock DT, Louis JM, Baber JL, Levens D, Clore GM. Braddock DT, et al. Nature. 2002 Feb 28;415(6875):1051-6. doi: 10.1038/4151051a. Nature. 2002. PMID: 11875576

8

NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter.

Huth JR, Yu L, Collins I, Mack J, Mendoza R, Isaac B, Braddock DT, Muchmore SW, Comess KM, Fesik SW, Clore GM, Levens D, Hajduk PJ. Huth JR, et al. Among authors: braddock dt. J Med Chem. 2004 Sep 23;47(20):4851-7. doi: 10.1021/jm0497803. J Med Chem. 2004. PMID: 15369388

9

Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke.

Albright RA, Ornstein DL, Cao W, Chang WC, Robert D, Tehan M, Hoyer D, Liu L, Stabach P, Yang G, De La Cruz EM, Braddock DT. Albright RA, et al. Among authors: braddock dt. J Biol Chem. 2014 Feb 7;289(6):3294-306. doi: 10.1074/jbc.M113.505867. Epub 2013 Dec 12. J Biol Chem. 2014. PMID: 24338010 Free PMC article.

10

ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy.

Albright RA, Stabach P, Cao W, Kavanagh D, Mullen I, Braddock AA, Covo MS, Tehan M, Yang G, Cheng Z, Bouchard K, Yu ZX, Thorn S, Wang X, Folta-Stogniew EJ, Negrete A, Sinusas AJ, Shiloach J, Zubal G, Madri JA, De La Cruz EM, Braddock DT. Albright RA, et al. Among authors: braddock aa, braddock dt. Nat Commun. 2015 Dec 1;6:10006. doi: 10.1038/ncomms10006. Nat Commun. 2015. PMID: 26624227 Free PMC article.

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