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Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression.
Cells. 2021 Sep 23;10(10):2516. doi: 10.3390/cells10102516.
Cells. 2021.
PMID: 34685496
Free PMC article.
Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity.
Ghallab A, Hassan R, Hofmann U, Friebel A, Hobloss Z, Brackhagen L, Begher-Tibbe B, Myllys M, Reinders J, Overbeck N, Sezgin S, Zühlke S, Seddek AL, Murad W, Brecklinghaus T, Kappenberg F, Rahnenführer J, González D, Goldring C, Copple IM, Marchan R, Longerich T, Vucur M, Luedde T, Urban S, Canbay A, Schreiter T, Trauner M, Akakpo JY, Olyaee M, Curry SC, Sowa JP, Jaeschke H, Hoehme S, Hengstler JG.
Ghallab A, et al. Among authors: brackhagen l.
J Hepatol. 2022 Jul;77(1):71-83. doi: 10.1016/j.jhep.2022.01.020. Epub 2022 Feb 5.
J Hepatol. 2022.
PMID: 35131407
Free PMC article.
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Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity.
Hassan R, Friebel A, Brackhagen L, Hobloss Z, Myllys M, González D, Albrecht W, Mohammed ESI, Seddek AL, Marchan R, Cadenas C, Cramer B, Humpf HU, Hartl L, Simbrunner B, Reiberger T, Trauner M, Hoehme S, Degen GH, Hengstler JG, Ghallab A.
Hassan R, et al. Among authors: brackhagen l.
Arch Toxicol. 2022 Nov;96(11):2967-2981. doi: 10.1007/s00204-022-03361-8. Epub 2022 Aug 13.
Arch Toxicol. 2022.
PMID: 35962801
Free PMC article.
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Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins.
Hassan R, Myllys M, Brackhagen L, Hobloss Z, González D, Seddek AL, Friebel A, Hoehme S, Marchan R, Trauner M, Hengstler JG, Ghallab A.
Hassan R, et al. Among authors: brackhagen l.
Arch Toxicol. 2022 Nov;96(11):3067-3076. doi: 10.1007/s00204-022-03353-8. Epub 2022 Sep 14.
Arch Toxicol. 2022.
PMID: 36102954
Free PMC article.
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Loss of bile salt export pump aggravates lipopolysaccharide-induced liver injury in mice due to impaired hepatic endotoxin clearance.
Remetic J, Ghallab A, Hobloss Z, Brackhagen L, Hassan R, Myllys M, Radun R, Mlitz V, Zhu C, Baumgartner M, Schrottmaier WC, Mussbacher M, Timelthaler G, Scharnagl H, Stojakovic T, Assinger A, Fuchs CD, Hengstler JG, Trauner M.
Remetic J, et al. Among authors: brackhagen l.
Hepatology. 2022 May;75(5):1095-1109. doi: 10.1002/hep.32289. Epub 2022 Jan 19.
Hepatology. 2022.
PMID: 34927748
Free PMC article.
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Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A.
Hassan R, González D, Hobloss Z, Brackhagen L, Myllys M, Friebel A, Seddek AL, Marchan R, Cramer B, Humpf HU, Hoehme S, Degen GH, Hengstler JG, Ghallab A.
Hassan R, et al. Among authors: brackhagen l.
Arch Toxicol. 2022 Dec;96(12):3349-3361. doi: 10.1007/s00204-022-03395-y. Epub 2022 Oct 13.
Arch Toxicol. 2022.
PMID: 36227364
Free PMC article.
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Increased sinusoidal export of drug glucuronides is a compensative mechanism in liver cirrhosis of mice.
Fendt R, Ghallab A, Myllys M, Hofmann U, Hassan R, Hobloss Z, González D, Brackhagen L, Marchan R, Edlund K, Seddek AL, Abdelmageed N, Blank LM, Schlender JF, Holland CH, Hengstler JG, Kuepfer L.
Fendt R, et al. Among authors: brackhagen l.
Front Pharmacol. 2023 Nov 20;14:1279357. doi: 10.3389/fphar.2023.1279357. eCollection 2023.
Front Pharmacol. 2023.
PMID: 38053838
Free PMC article.
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Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Mattsson J, Marschall HU, Hoehme S, Stirnimann G, Schwab M, Boor P, Amann K, Schmitz J, Bräsen JH, Rahnenführer J, Edlund K, Karpen SJ, Simbrunner B, Reiberger T, Mandorfer M, Trauner M, Dawson PA, Lindström E, Hengstler JG.
Ghallab A, et al. Among authors: brackhagen l.
J Hepatol. 2024 Feb;80(2):268-281. doi: 10.1016/j.jhep.2023.10.035. Epub 2023 Nov 7.
J Hepatol. 2024.
PMID: 37939855
Free PMC article.
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