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Page 1
Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study.
Wagner SJ, Reisenbüchler D, West NP, Niehues JM, Zhu J, Foersch S, Veldhuizen GP, Quirke P, Grabsch HI, van den Brandt PA, Hutchins GGA, Richman SD, Yuan T, Langer R, Jenniskens JCA, Offermans K, Mueller W, Gray R, Gruber SB, Greenson JK, Rennert G, Bonner JD, Schmolze D, Jonnagaddala J, Hawkins NJ, Ward RL, Morton D, Seymour M, Magill L, Nowak M, Hay J, Koelzer VH, Church DN; TransSCOT consortium; Matek C, Geppert C, Peng C, Zhi C, Ouyang X, James JA, Loughrey MB, Salto-Tellez M, Brenner H, Hoffmeister M, Truhn D, Schnabel JA, Boxberg M, Peng T, Kather JN. Wagner SJ, et al. Among authors: boxberg m. Cancer Cell. 2023 Sep 11;41(9):1650-1661.e4. doi: 10.1016/j.ccell.2023.08.002. Epub 2023 Aug 30. Cancer Cell. 2023. PMID: 37652006 Free PMC article.
Loss of CDX2 in colorectal cancer is associated with histopathologic subtypes and microsatellite instability but is prognostically inferior to hematoxylin-eosin-based morphologic parameters from the WHO classification.
Konukiewitz B, Schmitt M, Silva M, Pohl J, Lang C, Steiger K, Halfter K, Engel J, Schlitter AM, Boxberg M, Pfarr N, Wilhelm D, Foersch S, Tschurtschenthaler M, Weichert W, Jesinghaus M. Konukiewitz B, et al. Among authors: boxberg m. Br J Cancer. 2021 Dec;125(12):1632-1646. doi: 10.1038/s41416-021-01553-0. Epub 2021 Oct 6. Br J Cancer. 2021. PMID: 34616012 Free PMC article.
Morphology Matters: A Critical Reappraisal of the Clinical Relevance of Morphologic Criteria From the 2019 WHO Classification in a Large Colorectal Cancer Cohort Comprising 1004 Cases.
Jesinghaus M, Schmitt M, Lang C, Reiser M, Scheiter A, Konukiewitz B, Steiger K, Silva M, Tschurtschenthaler M, Lange S, Foersch S, Becker KF, Saur D, Friess H, Halfter K, Engel J, Boxberg M, Pfarr N, Wilhelm D, Weichert W. Jesinghaus M, et al. Among authors: boxberg m. Am J Surg Pathol. 2021 Jul 1;45(7):969-978. doi: 10.1097/PAS.0000000000001692. Am J Surg Pathol. 2021. PMID: 34105518
Tumour budding-based grading as independent prognostic biomarker in HPV-positive and HPV-negative head and neck cancer.
Stögbauer F, Beck S, Ourailidis I, Hess J, Poremba C, Lauterbach M, Wollenberg B, Buchberger AMS, Jesinghaus M, Schirmacher P, Stenzinger A, Weichert W, Boxberg M, Budczies J. Stögbauer F, et al. Among authors: boxberg m. Br J Cancer. 2023 Jun;128(12):2295-2306. doi: 10.1038/s41416-023-02240-y. Epub 2023 Apr 12. Br J Cancer. 2023. PMID: 37045906 Free PMC article.
Pre-operative cellular dissociation grading in biopsies is highly predictive of post-operative tumour stage and patient outcome in head and neck squamous cell carcinoma.
Jesinghaus M, Steiger K, Stögbauer F, Haller B, Kolk A, Straßen U, Pickhard A, Wirth M, Silva M, Budczies J, Becker von Rose A, Konukiewitz B, Kuhn P, Klinghammer K, Dapper H, Münch S, Combs SE, Weichert W, Boxberg M. Jesinghaus M, et al. Among authors: boxberg m. Br J Cancer. 2020 Mar;122(6):835-846. doi: 10.1038/s41416-019-0719-8. Epub 2020 Jan 15. Br J Cancer. 2020. PMID: 31937923 Free PMC article.
Mutational profiles of Brenner tumors show distinctive features uncoupling urothelial carcinomas and ovarian carcinoma with transitional cell histology.
Pfarr N, Darb-Esfahani S, Leichsenring J, Taube E, Boxberg M, Braicu I, Jesinghaus M, Penzel R, Endris V, Noske A, Weichert W, Schirmacher P, Denkert C, Stenzinger A. Pfarr N, et al. Among authors: boxberg m. Genes Chromosomes Cancer. 2017 Oct;56(10):758-766. doi: 10.1002/gcc.22480. Epub 2017 Jul 25. Genes Chromosomes Cancer. 2017. PMID: 28639280
Increased intraepithelial CD3+ T-lymphocytes and high PD-L1 expression on tumor cells are associated with a favorable prognosis in esophageal squamous cell carcinoma and allow prognostic immunogenic subgrouping.
Jesinghaus M, Steiger K, Slotta-Huspenina J, Drecoll E, Pfarr N, Meyer P, Konukiewitz B, Bettstetter M, Wieczorek K, Ott K, Feith M, Langer R, Weichert W, Specht K, Boxberg M. Jesinghaus M, et al. Among authors: boxberg m. Oncotarget. 2017 Jul 18;8(29):46756-46768. doi: 10.18632/oncotarget.18606. Oncotarget. 2017. PMID: 28657901 Free PMC article.
54 results