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Biallelic loss-of-function variants in PLD1 cause congenital right-sided cardiac valve defects and neonatal cardiomyopathy.
J Clin Invest. 2021 Mar 1;131(5):e142148. doi: 10.1172/JCI142148.
J Clin Invest. 2021.
PMID: 33645542
Free PMC article.
Crystal structure of human PLD1 provides insight into activation by PI(4,5)P2 and RhoA.
Bowling FZ, Salazar CM, Bell JA, Huq TS, Frohman MA, Airola MV.
Bowling FZ, et al.
Nat Chem Biol. 2020 Apr;16(4):400-407. doi: 10.1038/s41589-020-0499-8. Epub 2020 Mar 16.
Nat Chem Biol. 2020.
PMID: 32198492
Free PMC article.
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Structure and regulation of human phospholipase D.
Bowling FZ, Frohman MA, Airola MV.
Bowling FZ, et al.
Adv Biol Regul. 2021 Jan;79:100783. doi: 10.1016/j.jbior.2020.100783. Epub 2021 Jan 3.
Adv Biol Regul. 2021.
PMID: 33495125
Free PMC article.
Review.
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Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.
Li FL, Wu Z, Gao YQ, Bowling FZ, Franklin JM, Hu C, Suhandynata RT, Frohman MA, Airola MV, Zhou H, Guan KL.
Li FL, et al. Among authors: bowling fz.
EMBO J. 2022 Sep 1;41(17):e110698. doi: 10.15252/embj.2022110698. Epub 2022 Jul 17.
EMBO J. 2022.
PMID: 35844135
Free PMC article.
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