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Inhibition of LTβR signalling activates WNT-induced regeneration in lung.
Conlon TM, John-Schuster G, Heide D, Pfister D, Lehmann M, Hu Y, Ertüz Z, Lopez MA, Ansari M, Strunz M, Mayr C, Angelidis I, Ciminieri C, Costa R, Kohlhepp MS, Guillot A, Günes G, Jeridi A, Funk MC, Beroshvili G, Prokosch S, Hetzer J, Verleden SE, Alsafadi H, Lindner M, Burgstaller G, Becker L, Irmler M, Dudek M, Janzen J, Goffin E, Gosens R, Knolle P, Pirotte B, Stoeger T, Beckers J, Wagner D, Singh I, Theis FJ, de Angelis MH, O'Connor T, Tacke F, Boutros M, Dejardin E, Eickelberg O, Schiller HB, Königshoff M, Heikenwalder M, Yildirim AÖ. Conlon TM, et al. Among authors: boutros m. Nature. 2020 Dec;588(7836):151-156. doi: 10.1038/s41586-020-2882-8. Epub 2020 Nov 4. Nature. 2020. PMID: 33149305 Free PMC article.
Active Wnt proteins are secreted on exosomes.
Gross JC, Chaudhary V, Bartscherer K, Boutros M. Gross JC, et al. Among authors: boutros m. Nat Cell Biol. 2012 Oct;14(10):1036-45. doi: 10.1038/ncb2574. Epub 2012 Sep 16. Nat Cell Biol. 2012. PMID: 22983114
Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells.
Voloshanenko O, Erdmann G, Dubash TD, Augustin I, Metzig M, Moffa G, Hundsrucker C, Kerr G, Sandmann T, Anchang B, Demir K, Boehm C, Leible S, Ball CR, Glimm H, Spang R, Boutros M. Voloshanenko O, et al. Among authors: boutros m. Nat Commun. 2013;4:2610. doi: 10.1038/ncomms3610. Nat Commun. 2013. PMID: 24162018 Free PMC article.
Wnt signaling in cancer.
Zhan T, Rindtorff N, Boutros M. Zhan T, et al. Among authors: boutros m. Oncogene. 2017 Mar;36(11):1461-1473. doi: 10.1038/onc.2016.304. Epub 2016 Sep 12. Oncogene. 2017. PMID: 27617575 Free PMC article. Review.
MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer.
Zhan T, Ambrosi G, Wandmacher AM, Rauscher B, Betge J, Rindtorff N, Häussler RS, Hinsenkamp I, Bamberg L, Hessling B, Müller-Decker K, Erdmann G, Burgermeister E, Ebert MP, Boutros M. Zhan T, et al. Among authors: boutros m. Nat Commun. 2019 May 16;10(1):2197. doi: 10.1038/s41467-019-09898-0. Nat Commun. 2019. PMID: 31097693 Free PMC article.
Gut Microbiota-Derived Propionate Regulates the Expression of Reg3 Mucosal Lectins and Ameliorates Experimental Colitis in Mice.
Bajic D, Niemann A, Hillmer AK, Mejias-Luque R, Bluemel S, Docampo M, Funk MC, Tonin E, Boutros M, Schnabl B, Busch DH, Miki T, Schmid RM, van den Brink MRM, Gerhard M, Stein-Thoeringer CK. Bajic D, et al. Among authors: boutros m. J Crohns Colitis. 2020 Oct 5;14(10):1462-1472. doi: 10.1093/ecco-jcc/jjaa065. J Crohns Colitis. 2020. PMID: 32227170 Free PMC article.
Ageing, metabolism and the intestine.
Funk MC, Zhou J, Boutros M. Funk MC, et al. Among authors: boutros m. EMBO Rep. 2020 Jul 3;21(7):e50047. doi: 10.15252/embr.202050047. Epub 2020 Jun 21. EMBO Rep. 2020. PMID: 32567155 Free PMC article. Review.
384 results