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Page 1
Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids.
Janssen AWF, Houben T, Katiraei S, Dijk W, Boutens L, van der Bolt N, Wang Z, Brown JM, Hazen SL, Mandard S, Shiri-Sverdlov R, Kuipers F, Willems van Dijk K, Vervoort J, Stienstra R, Hooiveld GJEJ, Kersten S. Janssen AWF, et al. Among authors: boutens l. J Lipid Res. 2017 Jul;58(7):1399-1416. doi: 10.1194/jlr.M075713. Epub 2017 May 22. J Lipid Res. 2017. PMID: 28533304 Free PMC article.
SUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes.
van Diepen JA, Robben JH, Hooiveld GJ, Carmone C, Alsady M, Boutens L, Bekkenkamp-Grovenstein M, Hijmans A, Engelke UFH, Wevers RA, Netea MG, Tack CJ, Stienstra R, Deen PMT. van Diepen JA, et al. Among authors: boutens l. Diabetologia. 2017 Jul;60(7):1304-1313. doi: 10.1007/s00125-017-4261-z. Epub 2017 Apr 5. Diabetologia. 2017. PMID: 28382382 Free PMC article.
A role for TLR10 in obesity and adipose tissue morphology.
Boutens L, Mirea AM, van den Munckhof I, Doppenberg-Oosting M, Jaeger M, Hijmans A, Netea MG, Joosten LAB, Stienstra R. Boutens L, et al. Cytokine. 2018 Aug;108:205-212. doi: 10.1016/j.cyto.2018.03.021. Epub 2018 Apr 23. Cytokine. 2018. PMID: 29698883
Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells.
Lachmandas E, Beigier-Bompadre M, Cheng SC, Kumar V, van Laarhoven A, Wang X, Ammerdorffer A, Boutens L, de Jong D, Kanneganti TD, Gresnigt MS, Ottenhoff TH, Joosten LA, Stienstra R, Wijmenga C, Kaufmann SH, van Crevel R, Netea MG. Lachmandas E, et al. Among authors: boutens l. Eur J Immunol. 2016 Nov;46(11):2574-2586. doi: 10.1002/eji.201546259. Epub 2016 Sep 27. Eur J Immunol. 2016. PMID: 27624090 Free PMC article.
Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis.
Domínguez-Andrés J, Arts RJW, Ter Horst R, Gresnigt MS, Smeekens SP, Ratter JM, Lachmandas E, Boutens L, van de Veerdonk FL, Joosten LAB, Notebaart RA, Ardavín C, Netea MG. Domínguez-Andrés J, et al. Among authors: boutens l. PLoS Pathog. 2017 Sep 18;13(9):e1006632. doi: 10.1371/journal.ppat.1006632. eCollection 2017 Sep. PLoS Pathog. 2017. PMID: 28922415 Free PMC article.
Changes in gene expression associated with FTO overexpression in mice.
Merkestein M, McTaggart JS, Lee S, Kramer HB, McMurray F, Lafond M, Boutens L, Cox R, Ashcroft FM. Merkestein M, et al. Among authors: boutens l. PLoS One. 2014 May 19;9(5):e97162. doi: 10.1371/journal.pone.0097162. eCollection 2014. PLoS One. 2014. PMID: 24842286 Free PMC article.