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Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex.
Gruszczyk J, Grandvuillemin L, Lai-Kee-Him J, Paloni M, Savva CG, Germain P, Grimaldi M, Boulahtouf A, Kwong HS, Bous J, Ancelin A, Bechara C, Barducci A, Balaguer P, Bourguet W. Gruszczyk J, et al. Among authors: bous j. Nat Commun. 2022 Nov 16;13(1):7010. doi: 10.1038/s41467-022-34773-w. Nat Commun. 2022. PMID: 36385050 Free PMC article.
Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex.
Bous J, Fouillen A, Orcel H, Trapani S, Cong X, Fontanel S, Saint-Paul J, Lai-Kee-Him J, Urbach S, Sibille N, Sounier R, Granier S, Mouillac B, Bron P. Bous J, et al. Sci Adv. 2022 Sep 2;8(35):eabo7761. doi: 10.1126/sciadv.abo7761. Epub 2022 Sep 2. Sci Adv. 2022. PMID: 36054364 Free PMC article.
Frizzleds act as dynamic pharmacological entities.
Schulte G, Scharf MM, Bous J, Voss JH, Grätz L, Kozielewicz P. Schulte G, et al. Among authors: bous j. Trends Pharmacol Sci. 2024 May;45(5):419-429. doi: 10.1016/j.tips.2024.03.003. Epub 2024 Apr 8. Trends Pharmacol Sci. 2024. PMID: 38594145 Free article. Review.
Effect of evolocumab or ezetimibe added to moderate- or high-intensity statin therapy on LDL-C lowering in patients with hypercholesterolemia: the LAPLACE-2 randomized clinical trial.
Robinson JG, Nedergaard BS, Rogers WJ, Fialkow J, Neutel JM, Ramstad D, Somaratne R, Legg JC, Nelson P, Scott R, Wasserman SM, Weiss R; LAPLACE-2 Investigators. Robinson JG, et al. JAMA. 2014 May 14;311(18):1870-82. doi: 10.1001/jama.2014.4030. JAMA. 2014. PMID: 24825642 Clinical Trial.
20 results